| Japanese |
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| Title | 冠動脈再建術症例における上行大動脈内ニトログリセリン投与の冠血流量及び血行動態におよぼす影響 |
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| Authors | 五嶋良吉, 木下修*, 池垣淳一*, 小川恭一**, 鶴田宏昭**, 山本信一郎**, 岩井誠三*** |
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| Organization | 兵庫県立こども病院麻酔科, *兵庫県立姫路循環器病センター麻酔科, **兵庫県立姫路循環器病センター胸部外科, ***神戸大学医学部麻酔科 |
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| Journal | 循環制御 |
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| Volume | 6 |
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| Number | 4 |
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| Page | 511-515 |
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| Year/Month | 1985/ |
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| Article | 原著 |
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| Publisher | 日本循環制御研究会 |
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| Abstract | 「要旨」冠動脈再建術症例で術中ニトログリセリン直接投与による冠血流量及び血行動態への影響をしらべるために, 体外循環からの離脱前に心停止液注入ラインより1mgのニトログリセリンを投与した群6例(以下投与群)と非投与群6例でグラフト部冠血流量と周術期の血圧等の諸パラメータを比較検討した. 投与群と非投与群との間に年令, 体重, 身長, 術前心係数に有意差なく, グラフト部冠血流量は体外循環からの離脱前の測定で両群間に有意差はなかった. 投与群ではグラフト部冠血流量測定直後にニトログリセリンを注入したが, その前後での流量に有意差はなかった. また両群とも閉胸前にグラフト部冠血流量を測定し, 両群に有意差を認めた. 非投与群の心係数は手術前後で有意の増加を認めなかったが, 投与群では有意の増加を認めた. |
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| Practice | 基礎医学・関連科学 |
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| English |
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| Title | Effect of Nitroglycerin Administration through Aortic Root on Coronary Circulation and hemodynamics during Cardiopulmonary Bypass for Aorto-Coronary Bypass |
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| Authors | Ryokichi Goto, Osamu Kinosita*, Junichi Ikegaki*, Kyoichi Ogwa**, Hiroaki Tsuruta**, Shinichi Yamamoto**, Seizo Iwami*** |
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| Organization | *Department of Anesthesia, Kobe Children's Hospital Dept. of Anesth. Himeji Brain and Heart Center, **Dept. of Cardiovascular Surg., Himeji Brain and Heart Center, ***Dept. of Anesth. Kobe Univ. School of Medicine |
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| Journal | Circulation Control |
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| Volume | 6 |
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| Number | 4 |
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| Page | 511-515 |
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| Year/Month | 1985/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | We have investgated the effect of nitroglycerin (NTG) on coronary circulation, blood pressure and cardiac index during extracorporeal circulation in patients who were subjected to AC bypass. Twelve patients were divided into 2 groups : 1 mg of NTG was injected bolusly through aortic root in 6 patient prior to cessation from partial cardiopumonary bypass (NTG-group), and in other 6 patiens no NTG was injected (control group). In the both groups left anterior descending coronary (LAD) graft flow was measured and other hemodynamic paremeters were recorded. There were no significant difference between two groups in age, body weight, height, preoperative cardiac index and LAD graft flow measeured prior to NTG injection (NTG group) and to cessation from cardiopulmonary bypass. In the NTG group 1 mg of NTG was injected during the measurement of LAD flow, and no significant changes in the flow were observed following the NTG injection. The flow was measured again before the closure of sternal bone in the both groups, however, significant increase in the flow was revealed in the NTG group. |
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| Practice | Basic medicine |
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