Japanese
Title開心術に対するブトルファノール, ディアゼパム, 笑気, 酸素麻酔
Subtitle原著
Authors木下修*1, 奥谷龍*2, 池垣淳一*3, 五嶋良吉*4, 清成宣人*5
Authors(kana)
Organization*1宝塚市立病院麻酔科, *2兵庫医科大学麻酔科, *3神戸大学麻酔科, *4兵庫県立こども病院麻酔科, *5兵庫県立姫路循環器病センター麻酔科
Journal循環制御
Volume7
Number1
Page625-628
Year/Month1986/
Article原著
Publisher日本循環制御研究会
Abstract心房中隔欠損閉鎖術を無輸血で施行した成人男女10名に, 初回量40μg/kg(人工心肺中20μg/kg追加)のブトルファノールとディアゼパム, 笑気, 酸素麻酔を行ない, 血行動態およびストレスホルモンとしての血漿カテコラミン濃度の変化を検討した. 平均動脈圧は皮膚切開前, 送血管挿入時に有意に低下した以外著変なかった. 心拍数, 平均肺動脈圧, 肺動脈楔入圧には変化を認めなかった. 平均右房圧は漸増傾向であった. 血行動態的には安定した麻酔が得られたが, 血漿エピネフリン, ノルエピネフリンとも, 手術, 人工心肺中, 後に有意に増加し, ストレス反応としての血漿カテコラミンの上昇は防ぎ得なかった.
Practice基礎医学・関連科学
KeywordsButorphanol Tartrate, Open Heart Surgery, Hemodynamics, Plasma Catecholamine
English
TitleButorphanol-Diazepam-N2O-O2 Anesthesia for Open Heart Surgery
Subtitle
AuthorsOsamu KINOSHITA*1, Ryu OKUTANI*2, Junichi IKEGAKI*3, Ryokichi GOTO*4, Nobuto KIYONARI*5
Authors(kana)
Organization*1Department of Anesthesiology, Takarazuka City Hospital, *2Hyogo Medical College, *3Kobe University, School of Medicine, *4Kobe Children's Hospital, *5Himeji Brain and Heart Center
JournalCirculation Control
Volume7
Number1
Page625-628
Year/Month1986/
ArticleOriginal article
PublisherJapan Society of Circulation Control
AbstractThe changes of plasma catecholamine levels have been followed and studied, as the indicator of hemodynamic change and stress reaction, on 10 patients who had closure of ASD without blood transfusion, whose anesthesia was maintained butorphanol-diazepam-N2O-O2(initial dose of butorphanol 40μg/kg, 20μg/kg during cardiopulmonary bypass). The m-AP did show no significant changes except for the period of preincision of skin and aortic canulation. Heart rate, m-PAP, PCWP did not show any significant changes. M-RAP showed tendency of increase. This anesthesia seemed to provide stable hemodynamic status. However, both plasma epinephrine and norepinephrine, showed significant rise during surgery, cardiopulmonary bypass and after cardiopulmonary bypass, indicating that these elevations of catecholamine might be very possibilly due to the stress reaction.
PracticeBasic medicine
KeywordsButorphanol Tartrate, Open Heart Surgery, Hemodynamics, Plasma Catecholamine

【全文PDF】