| Japanese |
|---|
| Title | 諸臓器の毛細血管血流ならびに動静脈シャント血流に及ぼす急性出血および出血性ショックの影響 |
|---|
| Subtitle | 原著 |
|---|
| Authors | 矢野博文, 松本信夫, 福井明, 高折益彦 |
|---|
| Authors(kana) | |
|---|
| Organization | 川崎医科大学麻酔学教室 |
|---|
| Journal | 循環制御 |
|---|
| Volume | 7 |
|---|
| Number | 4 |
|---|
| Page | 1065-1071 |
|---|
| Year/Month | 1986/ |
|---|
| Article | 原著 |
|---|
| Publisher | 日本循環制御医学会 |
|---|
| Abstract | 毛細血管は通過しないと考えられる直径9μm microsphereを使用して, 急性出血, および出血性ショック時の諸臓器毛細血管血流の変動を検討するとともに, その静脈系への移行を観察することにより, 種々の臓器における動静脈シャント血流の変動をも観察した. 急性出血, および出血性ショック時には, おもに脾, および肝において, 心係数の低下と心拍出量分画の低下に基づく臓器血流量減少が認められた. しかしその代償として, その他の臓器血流量は比較的正常に維持され, 脳および副腎においてはむしろ血流量増加が認められた. また肝, 腎, 腹部臓器においては, 臓器内動静脈シャント率の低下が観察され, 動静脈シャント血管も循環血液量の低下時に, 末梢組織への酸素供給に対して防御的に機能していることが確認された. |
|---|
| Practice | 基礎医学・関連科学 |
|---|
| Keywords | hemorrhage, organ blood flow, distribution of cardiac output, arterio-venous shunt, microsphere |
|---|
| English |
|---|
| Title | Acute hemorrhage and organ microcirculation in dogs, particular reference to arterio-venous shunt |
|---|
| Subtitle | |
|---|
| Authors | Hirofumi Yano, Nobuo Matsumoto, Akira Fukui, Masuhiko Takaori |
|---|
| Authors(kana) | |
|---|
| Organization | Department of Anesthesiology, Kawasaki Medical School |
|---|
| Journal | Circulation Control |
|---|
| Volume | 7 |
|---|
| Number | 4 |
|---|
| Page | 1065-1071 |
|---|
| Year/Month | 1986/ |
|---|
| Article | Report |
|---|
| Publisher | Japan Society of Circulation Control |
|---|
| Abstract | The effect of hemorrhage on arterio-venous shunt in peripheral minute vessels was investigated in 9 dogs. Under either 12ml／kg or 24ml／kg hemorrhage, the radioactive isotope labeled, 9μm diametral microspheres were injected into the left atrium and the blood flow and the organ fraction of cardiac output were determined in the 14 organs. Arterio-venous shunt was measured by continuous collecting of venous blood for 40 seconds from the brain, liver, kidney, and splanchnic organs. During the hemorrhage, the blood flow into the spleen, liver, thyroid glands, and great omentum decreased markedly, paralleling to the decreases in not only cardiac output but also in its organ fraction. In other 10 organs, however, the blood flows were maintained comparably normal in spite of decrease of the cardiac output as a result of increase in the cardiac output fraction. The arterio-venous shunt was decreased in liver, kidney, and splanchnic organs under the hemorrhage, while it was mainteined unchanged in the brain. |
|---|
| Practice | Basic medicine |
|---|
| Keywords | hemorrhage, organ blood flow, distribution of cardiac output, arterio-venous shunt, microsphere |
|---|