| Japanese |
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| Title | 輸液負荷後における右心房変化に関する実験的研究 |
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| Authors | 福富悌, 高折益彦, 大隅昭幸, 福井明, 松本信夫 |
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| Organization | 川崎医科大学麻酔科学教室 |
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| Journal | 循環制御 |
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| Volume | 8 |
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| Number | 2 |
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| Page | 227-233 |
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| Year/Month | 1987/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | NLA麻酔下に, 24時間水分制限を行った雑種成犬21頭を各7頭づつ以下の3群に分けた. I群では麻酔導入後体液補正を行なわなかった. II群では15ml/kg・30minの輸液を行い, III群では30ml/kg・60minの輸液を行った. これらの群間の平均右房圧（mRAP）に差を認めなかった. そしてこれら全例に6ml/kg・5minの輸液負荷を行ったがmRAP上昇の程度に群間差を認めなかった. 上昇した右房圧が負荷前値までに低下する時間は, I群128, II群53, III群7分と推定された. 心係数はI群でのみ3.55±1.82から4.15±1.83l/min/m2へと上昇した. 中心血液量は3群とも差を認めず, 輸液負荷による変化も示さなかった. 体液バランス, とくに体内水分量動態はmRAP絶対値のみでは判定できず, その後の低下状態, とくに低下速度により, 概要が推測されることが認められた. |
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| Practice | 基礎医学・関連科学 |
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| English |
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| Title | Changes in right atrial pressure following fluid loading in dehydrated and hydrated dogs |
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| Subtitle | |
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| Authors | Osamu Fukutomi, Masuhiko Takaori, Akiyuki Ohsumi, Akira Fukui, Nobuo Matsumot |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology Kawasaki Medical School |
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| Journal | Circulation Control |
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| Volume | 8 |
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| Number | 2 |
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| Page | 227-233 |
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| Year/Month | 1987/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | Twenty−one adult mongrel dogs subjected to water restriction for 24 hours under NLA anesthesia were divided into 3 groups. In Group I, no adjustment of body fluid was performed. In Group II, 15ml／kg fluid was supplemented over a period of 30 minutes. In Group III, 30ml／kg fluid was supplemented over a period of 60 minutes. No difference was noted in the mean right atrial pressure （mRAP） among these 3 groups. On fluid loading of 6ml／kg over a peirod of 5 minutes, no difference in the degree of rise of mRAP was noted between these gruops. The time required for the mRAP to return to the preloading level was estimated to be 131 minutes in Group I, 50 minutes in Group II and 9 minutes in Group III. Cardiac index rose from 3.55±1.82 to 4.15±1.83l／min only in Group I. Central blood volume showed no difference among the 3 groups, and no change was noted in response to fluid loading. |
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| Practice | Basic medicine |
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| Keywords | fluid load, right atrial pressure, fluid distribution, venous compliance, dehydration |
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