Japanese |
Title | A−C Bypass術の麻酔 II. モルフィンおよび大量フェンタニール麻酔における術中循環動態 |
Subtitle | |
Authors | 神山洋一郎*, 福井聡*, 白石正治*, 長谷浩吉*, 里吉光子** |
Authors(kana) | |
Organization | *順天堂浦安病院麻酔科, **順天堂大学医学部麻酔科 |
Journal | 循環制御 |
Volume | 8 |
Number | 2 |
Page | 263-269 |
Year/Month | 1987/ |
Article | 原著 |
Publisher | 日本循環制御医学会 |
Abstract | A−C Bypass術症例でスワンガンツカテーテルを挿入し, 循環動態パラメーターを測定したもののうち, モルフィン麻酔(M群)7例, フェンタニール麻酔(F群)10例でその術中変化を比較した. M群はCI, LVSWIともに人工心肺前まで安定していたのに対し, F群ではCIはほぼ一定であったがLVSWIが心外膜切開時に28.5±6.9と突然有意に下降した(p<0.05). 人工心肺後はとくにM群でCI, LVSWIともに4.8±0.8, 55.9±9.3と有意に上昇した(P<0.05). TPRは全経過を通じてF群が常に高く, 術前値でM群が1,218±256であったのに対し, 1,495±266, 胸骨切開時1,597±496と高値で, 人工心肺後一時1,111±355と有意に下降した(p<0.05)が, ICUでは再び1,782±589とさらに高値を示した. PVRは術前値がM群F群でそれぞれ103.5±64.0, 56.2±21.6とバラつきが大きく, 人工心肺前はM群は減少傾向, F群は上昇傾向であった. 人工心肺後は身心とも一時低値を示したが, ICUでは上昇した. 心拍数, 収縮期血圧, RPPとあわせてみると, M群は一般に麻酔が浅く, 胸骨切開まで安定していたF群でも, 心外膜切開時に心拍数の上昇によるLVSWIの突然の下降がみられ, ここに問題点のあることがわかった. |
Practice | 基礎医学・関連科学 |
Keywords | |
English |
Title | Anesthesia for aorto−coronary bypass operation II. Comparative studies on hemodynamics between morphine and fentanyl anesthesia |
Subtitle | |
Authors | Yoichiro Kamiyama*, Satoshi Fukui*, Masaharu Shiraishi*, Kokichi Hase*, Mitsuko Satoyoshi** |
Authors(kana) | |
Organization | *Department of anesthesiology, Juntendo Urayasu Hospital, **Department of anesthesiology, School of medicine, Juntendo University |
Journal | Circulation Control |
Volume | 8 |
Number | 2 |
Page | 263-269 |
Year/Month | 1987/ |
Article | Original article |
Publisher | Japan Society of Circulation Control |
Abstract | Comparative studies on hemodynamics between morphine (1−1.5mg/kg) and fentanyl (75μg/kg) anesthesia for aorto−coronary bypass operation were carried out using the Swan−Ganz catheter method. 7 cases of morphine anesthesia (M group) and 10 cases of fentanyl anesthesia (F group) were randomly selected. Patients’ age, classifications, medications and operative course were similar in the two groups. CI (Cardiac Index) was constant in both groups before CPB (Cardio−Pulmonary Bypass). However, although LVSWI (Left Ventricular Stroke Work Index) was constant during pre−CPB in M group, a sudden signifcant decrease was observed in F group (control 38.0±11.1), 28.5±6.9 during pericardotomy (p<0.05), After CPB, CI and LVSWI of M group (4.8±0.8, 55.9±9.3) increased significantly (p<0.05). During all phases, TPR (Total Peripheral Resistance) values in F group (control 1,218±256, at sternotomy 1,597±496, at pericardotomy 1,541±477 and in ICU 1,782±589) were observed to be higher than in M group. |
Practice | Basic medicine |
Keywords | A−C bypass operation, morphine, fentanyl, hemodynamics |