| Japanese |
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| Title | 小児ハロセン緩徐導入時の循環変動におよぼすアトロピン前投薬の影響 |
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| Subtitle | 原著 |
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| Authors | 川名信*, 森田裕子*, 水口章*, 並木昭義* |
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| Organization | *札幌医科大学麻酔学教室 |
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| Journal | 循環制御 |
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| Volume | 10 |
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| Number | 3 |
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| Page | 423-427 |
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| Year/Month | 1989/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」小児ハロセン緩徐導入時循環変動におよぼすアトロピン前投薬の影響をThoracic Bioimpedance法を用い測定し検討を加えた. ハロセン2.5%10分間の吸入によリアトロピン0.015mg/kg投与群(A(+)群)と非投与群(A(-)群)で同様に心拍数は上昇し, 一回拍出量, 心拍出量は減少した. 血圧はA(-)群では有意に低下したが, A(+)群ではほとんど変化を示さなかった. また一回拍出量の抑制に関して平均値では両群間に差はなかった. しかし対照値の70%以下と強く抑制された症例の数はA(-)群で有意に多かった. 以上のことから, アトロピン前投薬は小児におけるハロセン緩徐導入時の循環抑制を緩和することが示唆された. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | Atropine, Halothane, Children, Hemodynamics |
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| English |
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| Title | The effcts of Atropine premedication on Hemodynamics at Halothane slow Induction for Pediatric Patients |
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| Authors | Shin Kawana, Yuko Morita, Akira Mizuguchi, Akiyoshi Namiki |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology Sapporo Medical College |
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| Journal | Circulation Control |
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| Volume | 10 |
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| Number | 3 |
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| Page | 423-427 |
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| Year/Month | 1989/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | The effects of atropine premedication on hemodynamics at halothane slow induction for pediatric patients were investigated with thoracic bioimpedance cardiometry which offers a noninvasive continuous measurement of heart rate (HR), stroke volume (SV) and cardiac output (CO). Forty-two healthy children ranged in age, from 1 yr. to 7 yr. were randomly assigned to atropinized group (n=23 ; A(+)) and non atropinized group (n=19 ; A(-)). A(+) group was given 0.015 mg/kg of atropine intramusculary an hour before induction and A(-) group was given nothing. Control hemodynamics were measured under 0.5% halothane and 67% nitrous oxide for three minutes. Afrer that, halothane was increased up to 2.5% then being kept for 10 minutes. At the control measurement, HR in A(+) group was higher than that in A(-) group. During measurement, both groups HR gradually increased accompanying depression of both SV and CO. Blood pressure of A(-) group decreased at the end of measurement, while A(+) group showed little changes. Although there was no significant difference between averaged SV depression in both groups, the number of children accompanied with severe SV depression (<70% of the control) was significantly high in A(-) group. In conclusion, halothane slow induction for children shows SV and CO depression, which can be attenuated by atropine premedication. |
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| Practice | Basic medicine |
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| Keywords | Atropine, Halothane, Children, Hemodynamis |
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