English
TitleWhole body oxygen consumption during aortic cross clamping and declamping in dogs anesthetized with isoflurane
Subtitle
AuthorsHarutaka Uematsu*1, Muneyasu Sha*2, Dwayne R.Westenskow*3
Authors(kana)
Organization*1Department of Anesthesiology Kawaigekabyouin, *2Department of Anesthesiology Teikyo University, *3University Utah
JournalCirculation Control
Volume11
Number3
Page339-345
Year/Month1990/
ArticleOriginal article
PublisherJapan Society of Circulation Control
AbstractHemodynamic and metabolic changes after aortic cross clamping and declamping of the abdominal aorta were studied in dogs under isoflurane anesthesia. During aortic cross clamping, cardiac output, whole body oxygen consumption, and saphenous vein O2 saturation decreased significantly (p<0.05) and arterial pressure, pulmonary arterial pressure, pulmonary arterial wedge pressure, and systemic vascular resistance increased (p<0.05) After aorta declamp arterial pressure, systemic vascural resistance and pulmonary arterial wedge pressure was decreased, although these changes were not significant to compare the pre-aortic clamping value. The correlation between percent change in cardiac output and oxygen consumption was poor after aorta clamping and declamping (r=0.35 p>0.05). The cause of the decrease in cardiac output which followed aortic clamping is not due to the changes of the oxygen consumption and partially explained by depression of myocardial performance. There was no relationship between the degree of reduction of arterial pressure after aonic declampihg and O2 debt of the ischemic tissue during aortic cross clamping (r=0.40 p>0.05). This means O2 debt calculated from oxygen consumption can not reflect the degree of the reduction of arterial pressure after aonic declamping.
PracticeBasic medicine
KeywordsAnesthesia, vascular surgery, Complication, Oxygen consumption

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