| Japanese |
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| Title | 左心ポンプ機能障害例にて動的運動時に末梢静脈圧が異常上昇を示す機序の推定 |
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| Subtitle | 原著 |
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| Authors | 伊藤裕康*, 石村耕二*, 湊口信也*, 浅野喜代治*, 井口壽也*, 今井洋子*, 越路正敏*, 各務雅夫*, 平川千里* |
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| Authors(kana) | |
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| Organization | *岐阜大学医学部第2内科 |
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| Journal | 循環制御 |
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| Volume | 11 |
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| Number | 4 |
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| Page | 489-496 |
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| Year/Month | 1990/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要約」軽症左心疾患患者にて, 軽度両下肢交互屈伸運動負荷(約2METS)を加え, 心係数の増加量(△CI), 平均肺動脈楔入圧の上昇量(△PAW), 末梢静脈圧の上昇量(△VP)を求め, △CI/△PAW>0.18L・min-1・M-2・mmHg-1は左心ポンプ機能良好(W群, n=22)を, △CI/△PAW≦0.18L・min-1・M-2・mmHg-1は左心ポンプ機能障害(P群, n=22)を表すと定義した. この時, △VPはW群とP群をよく弁別した, △VPがP群において異常高値を示す機序を解析する一方法として, 両群で実測した心係数-右房圧plotに, 仮説的右室拍出量曲線と仮説的体静脈還流曲線をfitせしめた. △VPが左心ポンプ機能障害例にて異常高値を示す機序として, 運動負荷による(1)右室拍出量曲線の劣化と(2)体静脈還流曲線の著しい右方移動が示唆された. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | 1) mild left-sided heart failure, 2) dynamic leg exercise, 3) plasma catecholamine concentration, 4) right ventricular output curve, 5) venous return curve |
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| English |
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| Title | Mechanisms of abnormally high peripheral venous pressure during mild supine leg exercise in patients with impaired pumping function of the left heart |
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| Subtitle | |
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| Authors | Hiroyasu Ito, Koji Ishimura, Sinya Minatoguchi, Kiyoji Asano, Hisaya Iguchi, Yoko Imai, Masatoshi Koshiji, Masao Kagami, Senri Hirakawa |
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| Authors(kana) | |
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| Organization | The 2nd Department of Internal Medicine Gifu University School of Medicine |
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| Journal | Circulation Control |
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| Volume | 11 |
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| Number | 4 |
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| Page | 489-496 |
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| Year/Month | 1990/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | In patients with mild left-sided heart disease, we performed mild exercise with alternate flexion and extension of both legs (about 2 METS) and obtained the increments of cardiac index (△CI), of tnean pulmonary artery wedge pressure (△PAW) and of peripheral venous pressure (△VP). When defining patients with △CI/△PAW>0.18 L・min-1・M-2・mmHg-1 as having well-functioning left heart (W group, n=22) and those with △CI/△PAW≦0.18 L・min-1・M-2・mmHg-1 as having poorly-functioning left heart (P group, n=22), △VP differentiated well the W group from the P group. To clarify the mechanisms of abnormally high △VP in P group, we plotted hypothetical right ventricular output curve and hypothetical venous return curve on a plane by taking the actually obtained CI on the ordinate and the actually obtained right atrial pressure on the abscissa. The mechanisms of the abnormally high △VP in P group were suggested to be (1) deterioration of the right ventricular output curve and (2) marked rightward shift of the venous return curve. |
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| Practice | Basic medicine |
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| Keywords | 1) mild left-sided heart failure, 2) dynamic leg exercise, 3) plasma catecholamine concentration, 4) right ventricular output curve, 5) venous return curve |
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