| Japanese |
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| Title | 左心補助人工心臓による心室細動下の循環維持 -関連度関数の手法を用いた交感神経活動電位の周波数解析による検討- |
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| Subtitle | 原著 |
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| Authors | 山家智之*, 仁田新一*, 片平美明*, 薗部太郎*, 永沼滋*, 秋保洋*, 柿沼義人*, 田中元直*, 三浦誠**, 内田直樹**, 佐藤直**, 毛利平**, 吉沢誠***, 竹田宏**** |
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| Authors(kana) | |
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| Organization | *東北大学抗酸菌病研究所電子医学, **東北大学医学部胸部外科, ***東北大学工学部通信工学科, ****東北大学工学部電気工学科 |
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| Journal | 循環制御 |
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| Volume | 12 |
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| Number | 1 |
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| Page | 69-76 |
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| Year/Month | 1991/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」交感神経活動の心拍性リズム発現に, 人工心臓駆動がどのような影響を与えているのかを検討するために, 左心補助人工心臓(LVAD)を装着した雑種成犬において交感神経活動中の心拍リズム成分とLVADリズム成分を, 自然心臓拍動下と心室細動下においてスペクトル解析法を用いて評価した. 心拍リズムのパワースペクトルの帯域パワー値及び動脈脈波と腎交感神経活動のコヒーレンスはLVADによる左心補助により有意に減少し, 心室細動下ではさらに減少した. またLVAD分時拍動数の周波数における帯域パワー値ならびにコヒーレンスは, LVAD駆動下ではいずれも増加した. 従ってLVAD駆動下では, 圧反射系の発振機構が圧受容体よりの入力に引き込まれているものと思われた. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | ventricular assist device (VAD), baroreceptor reflex, coherence spectra, power spectra, renal sympathetic nerve activity (RSNA) |
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| English |
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| Title | Spectral analysis of cardiac-related sympathetic nerve activity during left ventricular assistance under ventricular fibrillation |
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| Subtitle | |
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| Authors | Tomoyuki Yambe*, Shin-ichi Nitta*, Yoshiaki Katahira*, Taroh Sonobe*, Shigeru Naganuma*, Hiroshi Akiho*, Yoshito Kakinuma*, Motonao Tanaka*, Makoto Miura**, Naoki Uchida**, Naoshi Satoh**, Hitoshi Mohri**, Makoto Yoshizawa***, Hiroshi Takeda**** |
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| Authors(kana) | |
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| Organization | *Department of Medical Engineering and Cardiology Research Institute for Chest Diseases and Cancer Tohoku University, **Department of Thoracic and Cardiovascular Surgery School of Medicine Tohoku University, ***Department of Communication Engineering Faculty of Engineering Tohoku University, ****Department of Electrical Engineering Faculty of Engineering Tohoku University |
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| Journal | Circulation Control |
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| Volume | 12 |
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| Number | 1 |
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| Page | 69-76 |
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| Year/Month | 1991/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | To determine the effect of left ventricular assistance on cardiac related sympathetic activity, renal sympathetic nerve activity (RSNA) were analysed by power spectrum and coherence function during LV assistance under natural heart beating and ventricular fibrillation. Our TH-7B pneumatically driven sac type ventricular assist device was used in this experiment. In 7 dogs in this series, ventricular assist device (VAD) were inserted between the left atrium and the descending aorta. After the left frank was opened, bipolar electrode was attached to the left renal sympathetic nerve via retroperitoneal approach to detect the RSNA. VAD were driven at the rate of 50/mlin. Values of the squared coherence between the arterial pressure waveform and RSNA were measured at the same frequency of cardiac rhythm and VAD pumping rhythm. With the LVAD pumping, coherence at the cardiac rhythm was decreased and coherence at the VAD pumping rhythm was increased during natural heart beating and ventricular fibrillation. These results indicate that arterial pulse wave which was made by the LVAD assistance contributed to the postganglionic sympathetic activity. |
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| Practice | Basic medicine |
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| Keywords | ventricular assist device (VAD), baroreceptor reflex, coherence spectra, power spectra, renal sympathetic nerve activity (RSNA) |
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