| Japanese |
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| Title | 無輸血冠動脈再建術の戦術期における混合静脈酸素飽和度測定の意義 |
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| Subtitle | 原著 |
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| Authors | 新見能成*, 佐藤裕美*, 水嶋章郎*, 茅稽二* |
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| Authors(kana) | |
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| Organization | *順天堂大学医学部麻酔教室 |
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| Journal | 循環制御 |
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| Volume | 12 |
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| Number | 1 |
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| Page | 105-110 |
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| Year/Month | 1991/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」術中から術後, 無輸血で冠動脈再建術を施行した40例を対象に, 周術期における混合静脈酸素飽和度(SvO2)と他の酸素需給に関する諸因子の変動について研究した. 全測定について観察した場合も個々の症例ごとに観察した場合もSvO2と心拍出量(CO)のあいだにほとんど相関は認められなかった. 体外循環の希釈によるヘモグロビン濃度(Hb)の低下をCOの上昇が補い, 経過中酸素運搬能(DO2)は比較的一定に保たれた. 一方, 酸素消費量(VO2)の変化は大きく, SvO2はむしろVO2と相関する傾向を示した. 本研究のごとく比較的長い測定間隔では, SvO2はCOの指標とはならない. 一定の条件で, VO2の変動しない程度の短時間内の変化についてのみCOとの関係を考慮するべきである. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | mixed venous oxygen saturation, cardiac output, coronary artery bypass grafting, oxygen consumption |
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| English |
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| Title | Correlation between Mixed Venous Oxygen Saturation and Hemodynamic Variables in Cardiac Surgical Patients |
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| Subtitle | |
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| Authors | Yoshinari Niimi, Hiromi Sato, Akio Mizushima, Keiji Kaya |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology Juntendo University School of Medicine |
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| Journal | Circulation Control |
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| Volume | 12 |
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| Number | 1 |
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| Page | 105-110 |
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| Year/Month | 1991/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | The correlation between changes in mixed venous oxygen saturation (SvO2) and oxygen transport variables was examined in 40 patients undergoing coronary artery bypass grafting without blood transfusion. Hemodynamic measurements were conducted and arterial and mixed venous samples obtained at 7 specified times：4 times during operation and 3 times during the postoperative period. Decrease in hemoglobin concentration due to hemodilution during cardiopulmonary bypass was found to be accompanied by compensating increase in cardiac output. Oxygen transport (DO2) was maintained relatively constant throughout the study. Oxygen consumption (VO2) increased more during the prebypass period by about 30% after cardiopulmonary bypass, and 60% in ICU. It thus follows that SvO2 is correlated with none of the hemodynamic variables of oxygen transport including cardiac output but rather with VO2. SvO2 measurement over relatively long intervals is thus concluded not to be usable predicting for cardiac output. However, it should serve to provide some indication of cardiac output when SvO2 drops rapidly as to prevent change in VO2. |
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| Practice | Basic medicine |
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| Keywords | mixed venous oxygen saturation, cardiac output, coronary artery bypass grafting, oxygen consumption |
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