| English |
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| Title | Influence of Anesthesia on Ischemic Myocardium |
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| Subtitle | (special edition) International Symposium on Ischemic Heart and Anesthesia |
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| Authors | Hideaki Tsuchida, Satoshi Fujita, Akiyoshi Namiki |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology,Sapporo Medical College |
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| Journal | Circulation Control |
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| Volume | 13 |
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| Number | 3 |
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| Page | 405-411 |
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| Year/Month | 1992/ |
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| Article | Report |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | There still remains a controversy whether anesthesia per se affects the course of myocardial ischemia.1) Most anesthetics depress myocardial contractility and decrease blood pressure and heart rate in humans and in experimental animals. These changes can improve the myocardial oxygen supply/demand relationship and relieve myocardial ischemia in the compromised myocardium. For example, Bland et al. reported that halothane decreased the severity of experimentally-induced acute myocardial ischemia in non-failing canine heart, monitoring ST segment changes by epicardial ECG.2) Vik-Mo et al. also demonstrated that thoracic epidural anesthesia (TEA) had a favorable effect on acute ischemic myocardium according to the same criterion.3) Since the attenuation of the ST increase induced by the epidural anesthesia dissappeared after the decreased heart rate and blood pressure had been restored to the control, pre-TEA levels by atrial pacing and phenylephrine infusion, they concluded that reduced myocardial activity was the main factor in relieving myocardial ischemia. |
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| Practice | Basic medicine |
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