| Japanese |
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| Title | 心室の可変弾性体モデルによる血行力学の理論的研究 |
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| Subtitle | 原著 |
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| Authors | 平山博史, 福山裕三 |
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| Organization | 旭川医科大学公衆衛生学教室 |
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| Journal | 循環制御 |
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| Volume | 13 |
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| Number | 3 |
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| Page | 449-456 |
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| Year/Month | 1992/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 菅らの可変弾性体モデルによる心臓の力学的表現と動脈系をウィンドケッセルモデルで表現し体循環の統合的解析を理論的に行なった. 心臓は可変コンデンサを基本的収縮要素とし圧欠損を近似する目的で内部抵抗と直列受動的弾性を含めた. ウィンドケッセルモデルは血流抵抗, コンプライアンス, 弁抵抗とした. これらを電気的等価回答で表わし連立線形微分, 積分方程式を数値的に解いた. 再現された血圧波形は生理的であった. 最大動脈血圧, 心内圧は血流抵抗の増加で増大し大動脈コンプライアンス, 弁抵抗, 心室内抵抗の増加で減少した. 大動脈拡張期血圧の変化もよく反映された. 本モデルは心臓を含む体循環を全体として表現することができる. |
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| Practice | 基礎医学・関連科学 |
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| English |
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| Title | A Theoretical Analysis of Hemodynamics by Time Varying Elastance Model of Ventricle |
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| Subtitle | Original |
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| Authors | H.Hirayama, Y.Fukuyama |
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| Authors(kana) | |
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| Organization | Department of Public Health,Asahikawa Medical College |
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| Journal | Circulation Control |
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| Volume | 13 |
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| Number | 3 |
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| Page | 449-456 |
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| Year/Month | 1992/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | Although some disagreements1,2) still exist about the reliability of load independency of the E(t) (the instantaneous pressure-volume ratio) of ventricle3), we can never find any other superior physiological comprehensive model or concept of the ventricle to describe the dynamic properties of whole heart. As a result, we prefer to utilize this elastance model to characterize and analyze the total behavior of ventricle instead of mechanical concept for whole heart such as constant flow pump or pressure pump. Nevertheless the ventricle was illustrated by the elastance model, we can not catch the total feature of interaction of ventricle-arterial system. Because no associated theoretical model had been proposed in which ventricle was expressed by the time varying elastance and arterial system was described by simple comprehensive model simultaneously. In the present study we constructed a theoretical physiological model with time varying elastance as a heart and with Wind Kessel model as arterial system to describe the total behavior of cardiovascular system Present analysis was confined to 1) reconstruct physiological pressure curves, 2) quantitive analysis of effects of arterial system parameters on the maximum arterial and ventricular pressures, and 3) analyze the effects of diastolic arterial pressure on these pressures. |
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| Practice | Basic medicine |
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