Japanese
Title心拍出量変化と動脈血炭酸ガス分圧変化の関係
Subtitle原著
Authors坂田正策*, 松本幸久*, 加藤道久**, 樋口精一*, 斎藤隆雄*
Authors(kana)
Organization*徳島大学医学部附属病院手術部, **徳島大学医学部附属病院集中治療部
Journal循環制御
Volume14
Number4
Page531-535
Year/Month1993/
Article原著
Publisher日本循環制御医学会
Abstract「要旨」GOE(エンフルレン)麻酔犬にドパミン, ニトログリセリン, プロスタグランディンE1および脱血の干渉を負荷し, 一定呼吸下におげる心拍出量(CO)変化とPaCO2変化の関係と, PETCO2によるこの関係の臨床応用について調査した. 各干渉によるCOの変動幅は-40％から+77％に範囲した. CO変化とPaCO2変化は定性的また定量的にも密接に相関し, 両者間で直線関係が示された. CO変化とPETCO2変化の関係も同様であった. 以上より, 換気が一定の条件で, 麻酔中に起こりうる程度のCO変動幅ではCO変化はPaCO2変化と比例関係にあり, 臨床的には死腔効果が増大する肺換気血流不均衡時を除いてPETCO2の監視によりCO変化を評価することが可能であると思われる.
Practice基礎医学・関連科学
Keywordscardiac output, arterial carbon dioxide tension, end-expiratory carbon dioxide tension
English
TitleRelationship between Changes in Cardiac Output and in Arterial Blood Gas Tension
Subtitle
AuthorsSeisaku Sakata, Yukihisa Matsumoto, Michihisa Kato, Seiichi Higuchi, Takao Saito
Authors(kana)
OrganizationDepartment of Anesthesiology,Tokushima University School of Medicine
JournalCirculation Control
Volume14
Number4
Page531-535
Year/Month1993/
ArticleOriginal article
PublisherJapan Society of Circulation Control
AbstractThis study was performed to investigate the relationship between changes in cardiac output (CO) and in arterial carbon dioxide tension (PaCO2), and the usefulness of end-expiratory carbon dioxide tension (PETCO2) as an estimate of CO in six nitrous oxide enflurane-anesthetized dogs under constant minute ventilation. Heart rate, arterial blood pressure, CO and blood and expiratory gas tensions were observed before and after administrations of dopamine, nitroglycerin and prostaglandin E1, and controlled bleeding. In 22 of 27 observations, the change in CO directionally coresponded with that in PaCO2 (p<0.01). The change in CO highly correlated to that in PaCO2 (r=0.793). In 25 of 27 observations, CO changed in accordance with the direction of the PETCO2 change (p<0.001). The change in CO closely correlated to that in PETCO2, too (r=0.855). It is seemed that the change in CO is linearly related to that in PaCO2 in the common anesthetic management, and that the change in CO can be evaluated with the change in PETCO2 in place of PaCO2 except in case of ventilation-perfusion mismatch which brings about the increase of dead space ventilation.
PracticeBasic medicine
Keywordscardiac output, arterial carbon dioxide tension, end-expiratory carbon dioxide tension

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