| Japanese |
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| Title | 心拍出量および酸素消費量のPaCO2変動への寄与度 |
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| Subtitle | 原著 |
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| Authors | 松本幸久, 坂田正策 |
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| Organization | 徳島大学医学部附属病院手術部 |
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| Journal | 循環制御 |
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| Volume | 15 |
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| Number | 1 |
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| Page | 94-99 |
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| Year/Month | 1994/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」一定の換気条件下に, ハロタン(H)およびセボフルラン(S)の吸入濃度を段階的に上昇させ, 心拍出量(CO)および酸素消費量(VO2)の変化と動脈血炭酸ガス分圧(PaCO2)との関係を調べるとともに, 両麻酔薬間での比較を行った. HおよびSの吸入濃度上昇にしたがって, CO, VO2, PaCO2は低下した. H, Sともに, COの変化量とPaCO2の変化量およびVO2の変化量とPaCO2の変化量の間には, 有意な相関と有意な回帰直線が得られたが, 後者に比べ前者の方が密接性がより高かった. HとSの比較では, 明かな差は認められなかった. 以上より, HおよびSの麻酔深度の変動によるPaCO2の変動は, VO2の変化に比べ, COの変化により強く依存すると思われた. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | Cordiac output, oxygen consumption, arterial dioxide tension, halothane, sevoflurane |
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| English |
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| Title | Effect of Changes in Cardiac Output and Oxygen Consumption on Arterial Carbon Dioxide Tension |
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| Authors | Yukihisa Matsumoto, Seisaku Sakata |
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| Authors(kana) | |
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| Organization | Department of Surgical Center,Tokushima University School of medicine |
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| Journal | Circulation Control |
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| Volume | 15 |
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| Number | 1 |
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| Page | 94-99 |
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| Year/Month | 1994/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | In 8 mongrel dogs, halothane and sevoflurane were administered during constant ventilation, increasing inspired concentration stepwise from 0 to 0.7, 1.4 and 2.1 MAC to examine the effect of changes in cardiac output (CO) and oxygen consumption (VO2) on arterial carbon dioxide tension (PaCO2) and also to make comparisons between the two anesthetics. With each increase in inspired concentration of halothane and sevoflurane, CO, VO2 and PaCO2 all decreased. Significant correlation and significant regression line were observed in both halothane and sevoflurane between volume of change in CO (ΔCO) and volume of change in PaCO2 (ΔPaCO2) and between volume of change in VO2 (ΔVO2) and ΔPaCO2. However, closeness in relationship between ΔCO and ΔPaCO2 was greater than that between ΔVO2 and ΔPaCO2. In comparisons between halothane and sevoflurane, no significant differences were seen in CO, VO2 or PaCO2. Nor were there observed any large differences in correlation coefficient or in regression equation between ΔCO and ΔPaCO2 and between ΔVO2 and ΔPaCO2. From the above, changes in PaCO2 resulting from changes in depth of halothane and sevoflurane anesthesia are considered to be more dependent on changes in CO than changes in VO2. |
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| Practice | Basic medicine |
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| Keywords | Cordiac output, oxygen consumption, arterial dioxide tension, halothane, sevoflurane |
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