| Japanese |
|---|
| Title | 終末呼吸陽圧呼吸の臓器血液量におよぼす影響―腹腔内圧の影響― |
|---|
| Subtitle | 原著 |
|---|
| Authors | 福井明, 高折益彦, 木村健一, 藤田喜久 |
|---|
| Authors(kana) | |
|---|
| Organization | 川崎医科大学麻酔科学教室 |
|---|
| Journal | 循環制御 |
|---|
| Volume | 15 |
|---|
| Number | 2 |
|---|
| Page | 249-257 |
|---|
| Year/Month | 1994/ |
|---|
| Article | 原著 |
|---|
| Publisher | 日本循環制御医学会 |
|---|
| Abstract | 「要旨」調節呼吸されたイヌにPEEPと腹腔内圧を負荷し, これによる循環血液量, 頭部, 胸部, 肝部, 脾部, 右大腿部の血液量の変化を経時的に測定した. この結果PEEPを5, 10, 15cmH2Oと上昇させるにしたがって, 動脈血圧は低下し, 循環血液量と胸部の血液量は減少, 反対に肝部, 脾部, 大腿部の血液量は増加した. とくに肝部における増加率が最大であった. この際腹腔内圧を0, 10, 20cmH2Oと上昇させるにしたがって, PEEP時の循環血液量減少と大腿部の血液量の増加とが認められなくなった. またPEEPによる胸部の血液量減少, 肝部, ならびに脾部血液量の増加は腹腔内圧 20cmH2Oでそれぞれ抑制された. 頭部血液量はいずれの影響も受けなかった. したがってPEEP時における腹腔内圧負荷はPEEPによる循環血液量の減少を抑制し, かつその各臓器への分布を正常に近づけることが認められた. |
|---|
| Practice | 基礎医学・関連科学 |
|---|
| Keywords | positive end expiratory pressure, organ blood flow, intraabdominal pressure, radionuclide scintilating volumetnic method |
|---|
| English |
|---|
| Title | The Effect of Positive End-expiratory Pressure on the Organ Blood Volume Modified by The Intraabdominal Pressure |
|---|
| Subtitle | |
|---|
| Authors | Fukui,A., Takaori,M., Kimura,K., Fujita,Y. |
|---|
| Authors(kana) | |
|---|
| Organization | Department of Anesthesiology,Kawasaki Medical School |
|---|
| Journal | Circulation Control |
|---|
| Volume | 15 |
|---|
| Number | 2 |
|---|
| Page | 249-257 |
|---|
| Year/Month | 1994/ |
|---|
| Article | Original article |
|---|
| Publisher | Japan Society of Circulation Control |
|---|
| Abstract | 「Abstract」Changes in the circulating blood volume and several organ blood volumes, i.e cranial, thoracic, hepatic, splenic and skeletal muscle (femoral adductors) blood volume, were observed serially by radionuclide scintillating volumetric method in dogs which were ventilated mechanically with 5, 10, 15cm H2O PEEP or without. Then abdomen of the animals was compressed with an air-tourniquet and their intraabdominal pressure (IAP) was elevated by 10 or 20 cmH2O. Again changes in the circulating blood volume and the organ blood volumes were observed in the same fashion with or without the PEEP. As results, the circulating blood volume decreased with PEEP of 10 or 15 cmH2O associated with the normal IAP but it remained unchanged associated with the elevated IAP. The thoracic blood volume also decreased under higher PEEP with the normal IAP. However its decreases were minimized even under higher PEEP when the IAP was elevated. The hepatic and splenic blood volume increased under the PEEP associated either with or without the elevated IAP. However these changes were less in the animals with the elevated IAP. Similarly increases of blood volume in the skeletal muscle under the PEEP were less associated with the elevated IAP than those with the normal IAP. Incidentally cardiac output decreased under the PEEP either with or without the elevated IAP. Therefore the above data showed that the deliberate elevation of IAP may maintain the organ blood volume more physiologically even under intermittent positive pressure ventilation with the PEEP. This technique, compression on the abdomen, may be applied for patient in whom splanchnic congestion is suspected under some shock states, e.g. endotoxin shock, and who are ventilated mechanically with high PEEP. |
|---|
| Practice | Basic medicine |
|---|
| Keywords | positive end expiratory pressure, organ blood flow, intraabdominal pressure, radionuclide scintilating volumetnic method |
|---|