| Japanese |
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| Title | 肝切除時の肝循環, 肝酸素代謝に及ぼすイソフルランの影響 |
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| Subtitle | 原著 |
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| Authors | 菅井実*, 黒木恭子*, 林和人*, 宮崎孝**, 松本延幸*, 堀孝郎* |
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| Authors(kana) | |
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| Organization | *埼玉医科大学麻酔学教室, **埼玉医科大学第1生化学教室 |
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| Journal | 循環制御 |
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| Volume | 16 |
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| Number | 1 |
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| Page | 59-63 |
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| Year/Month | 1995/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」雑種イヌ12頭を使い, イソフルラン(ISO)麻酔にて, 肝切除前後の肝循環動態と肝酸素需給動態に及ぼす影響を比較検討した. この結果, 肝切除術後に著明な肝循環および肝酸素代謝の抑制は起こらず, 特に門脈血流量(PVBF)がよく維持される傾向にあった. ISOはPVBFを良く維持する麻酔薬と考えられており1)〜3), 肝切除時にsplanchnic sequestrationを抑制し, 肝循環, 肝酸素代謝及び全身循環を良く維持する可能性が示唆された. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | 肝切除術, 肝循環, イソフルラン, Hepatolobectomy, Hepatic circulation, Isoflurane |
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| English |
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| Title | The Effect of Isoflurane on the Hepatic Circulation and Oxygen Metabolism during hepatolobectomy in Dogs. |
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| Authors | Minoru Sugai, Kyouko Kuroki, Kazuto Hayashi, Takashi Miyazaki*, Nobuyuki Matsumoto, Takao Hori |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology, Saitama Medical School, *First Department of Biochemistry, Saitama Medical School |
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| Journal | Circulation Control |
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| Volume | 16 |
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| Number | 1 |
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| Page | 59-63 |
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| Year/Month | 1995/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | The present study was undertaken in order to clarify the effect of isoflurane on hepatic circulation and hepatic oxygen metabolism in the case of hepatolobectomy in dogs. Hepatic blood flow was measured by electromagnetic flowmeter during the experiment. isoflurane decreased MVR (mesenteric vascular resistance) following hepatolobectomy and well maintained PVBF(portal venous blood flow). These results suggest that isoflurane dose not cause splanchic sequestration after hepatolobectomy, and maintains hepatic circulation, hepatic oxygen metabolism and systemic circulation well even after hepatolobectomy. |
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| Practice | Basic medicine |
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| Keywords | Hepatolobectomy, Hepatic circulation, Isoflurane |
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