| Japanese |
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| Title | イソフルランによる低血圧麻酔が内分泌, 代謝系に及ぼす影響―セボフルランとの比較― |
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| Subtitle | 原著 |
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| Authors | 小堀正雄, 細山田明義 |
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| Authors(kana) | |
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| Organization | 昭和大学医学部麻酔学教室 |
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| Journal | 循環制御 |
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| Volume | 16 |
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| Number | 4 |
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| Page | 514-519 |
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| Year/Month | 1995/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」ASA分類I度の鼓室形成術を対象に揮発性麻酔薬により収縮期血圧80〜90mmHgを目標とする低血圧麻酔を行い, 内分泌, 代謝系に及ぼす影響をイソフルラン(GOI群), セボフルラン(GOS群)で比較検討した. その結果, 両群とも低血圧麻酔中の血漿エピネフリン値, コルチゾール値は減少したが, ノルエピネフリン値は増加した. また, 血中乳酸値, 血糖値, 遊離脂肪酸も低血圧麻酔中に増加し, 両群間に差が認められなかった. しかし, 低血圧維持はGOS群では17例中8例でセボフルラン濃度を5.0%としても目標血圧に達っしなかったが, GOI群は全例可能であり低血圧麻酔が容易であった. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | Hypotensive anesthesia, Isoflurane, Sevoflurane, Endocrinic function, Metabolic function |
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| English |
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| Title | Influence of Hypotensive Anesthesia Using Isoflurane on Endocrine−metabolic Functions ―A Comparison with Sevoflurane― |
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| Subtitle | |
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| Authors | Masao Kobori, Akiyoshi Hosoyamada |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology, School of Medicine, Showa University |
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| Journal | Circulation Control |
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| Volume | 16 |
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| Number | 4 |
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| Page | 514-519 |
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| Year/Month | 1995/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | In the present study, we determind the influences of hypotensive anesthesia using nitrous oxideoxgen− isoflurane anesthesia (GOI) and nitrous oxide− oxgen− sevoflurane anesthesia (GOS) on functions of the circulatory and the endocrine−metabolic systems. Systolic blood pressure was maintained of between 80 and 90mmHg. In all of the cases GOI anesthesia (GOI− group) hypotensive state could easily be maintained, while in about half of the caces anesthesized with GOS (GOS− group) it was difficult main the hypotensive state. No significant increase in heart rate was noted in GOI group during hypotensive anesthesia, while a significant increase in heart rate was obtained in GOS group. Serum epinephrine decreased in both groups, while serum norepinephrine and cortisol levels increased similarly for both groups during hypotensive anesthesia. Lactic acid and L/P increased significantly in both groups. Blood glucose and non− esterified fatty acid increased significantly during hypotensive anesthesia in both groups. There was no difference in endocrine−metabolic functions under induced hypotensive anesthesia between GOI and GOS groups. However, the hypotensive state could be maintained more easily in GOI group than in GOS group. (Circ Cont 16：514〜519, 1995) |
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| Practice | Basic medicine |
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| Keywords | Hypotensive anesthesia, Isoflurane, Sevoflurane, Endocrinic function, Metabolic function |
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