Japanese |
Title | クモ膜下出血(SAH)患者における血圧とレニン−アンギオテンシン系の変動について |
Subtitle | 原著 |
Authors | 池田一美, 池田寿昭, 杉正俊 |
Authors(kana) | |
Organization | 東京医科大学八王子医療センター 麻酔科 |
Journal | 循環制御 |
Volume | 16 |
Number | 4 |
Page | 549-555 |
Year/Month | 1995/ |
Article | 原著 |
Publisher | 日本循環制御医学会 |
Abstract | 「要旨」我々は20例のクモ膜下出血(SAH)患者について, 術後の血圧と, レニン−アンギオテンシン系(RAS), 心房性Na利尿ペプチド(ANP)及びアルドステロンの変化について検討した. 血漿レニン活性は第3病日より, 血中アンギオテンシンI, II濃度は第7病日より有意に増加し, 第14病日まで高値が続いた. ANPは第3〜7病日には有意に増加, 第14病日には, ほぼ対照値にもどった. アルドステロンに有意の変化は無く, 血清Na濃度も正常範囲内であった. RAS系が活性化したにもかかわらず, 血圧に有意の変化は無く, 直接の相関はみられなかった. これはANPによる降圧作用が影響したのではないかと推察された. |
Practice | 基礎医学・関連科学 |
Keywords | Subarachnoid hemorrhage, Renin angiotensin substances, A-type natriuretic peptide Aldosterone, Blood pressure |
English |
Title | The Changes in Blood Pressure and Renin-angiotensin Substances in the Patients with Subarachnoid Hemorrhage |
Subtitle | |
Authors | Kazumi Ikeda, Toshiaki Ikeda, Masatoshi Sugi |
Authors(kana) | |
Organization | Department of Anesthesiology, Hachioji Medical Center of Tokyo Medical College |
Journal | Circulation Control |
Volume | 16 |
Number | 4 |
Page | 549-555 |
Year/Month | 1995/ |
Article | Original article |
Publisher | Japan Society of Circulation Control |
Abstract | We evaluated the changes in blood pressure, plasma renin activity (PRA), serum concentration of angiotentsin I II (AT-I II), aldosterone, A-type natriuretic peptide (ANP), in the twenty patients after clipping operation. PRA was observed singnificant increase after 7 th day and serum concentration of AT I II were observed singnificant increase after 3 rd day. All of them were showed high values until 14th day after operation, Serum concentration of aldosterone and Na were observed no significant change in this study. We concluded that renin-angiotensin system and ANP were increased after 3 rd day after operation that was not concerned with change in blood pressure. (Circ Cont 16:549〜555, 1995) |
Practice | Basic medicine |
Keywords | Subarachnoid hemorrhage, Renin angiotensin substances, A-type natriuretic peptide Aldosterone, Blood pressure |