Japanese
Titleクモ膜下出血(SAH)患者における血圧とレニン−アンギオテンシン系の変動について
Subtitle原著
Authors池田一美, 池田寿昭, 杉正俊
Authors(kana)
Organization東京医科大学八王子医療センター 麻酔科
Journal循環制御
Volume16
Number4
Page549-555
Year/Month1995/
Article原著
Publisher日本循環制御医学会
Abstract「要旨」我々は20例のクモ膜下出血(SAH)患者について, 術後の血圧と, レニン−アンギオテンシン系(RAS), 心房性Na利尿ペプチド(ANP)及びアルドステロンの変化について検討した. 血漿レニン活性は第3病日より, 血中アンギオテンシンI, II濃度は第7病日より有意に増加し, 第14病日まで高値が続いた. ANPは第3〜7病日には有意に増加, 第14病日には, ほぼ対照値にもどった. アルドステロンに有意の変化は無く, 血清Na濃度も正常範囲内であった. RAS系が活性化したにもかかわらず, 血圧に有意の変化は無く, 直接の相関はみられなかった. これはANPによる降圧作用が影響したのではないかと推察された.
Practice基礎医学・関連科学
KeywordsSubarachnoid hemorrhage, Renin angiotensin substances, A-type natriuretic peptide Aldosterone, Blood pressure
English
TitleThe Changes in Blood Pressure and Renin-angiotensin Substances in the Patients with Subarachnoid Hemorrhage
Subtitle
AuthorsKazumi Ikeda, Toshiaki Ikeda, Masatoshi Sugi
Authors(kana)
OrganizationDepartment of Anesthesiology, Hachioji Medical Center of Tokyo Medical College
JournalCirculation Control
Volume16
Number4
Page549-555
Year/Month1995/
ArticleOriginal article
PublisherJapan Society of Circulation Control
AbstractWe evaluated the changes in blood pressure, plasma renin activity (PRA), serum concentration of angiotentsin I II (AT-I II), aldosterone, A-type natriuretic peptide (ANP), in the twenty patients after clipping operation. PRA was observed singnificant increase after 7 th day and serum concentration of AT I II were observed singnificant increase after 3 rd day. All of them were showed high values until 14th day after operation, Serum concentration of aldosterone and Na were observed no significant change in this study. We concluded that renin-angiotensin system and ANP were increased after 3 rd day after operation that was not concerned with change in blood pressure. (Circ Cont 16:549〜555, 1995)
PracticeBasic medicine
KeywordsSubarachnoid hemorrhage, Renin angiotensin substances, A-type natriuretic peptide Aldosterone, Blood pressure

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