| Japanese |
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| Title | 循環停止中の局所脳内酸素飽和度の変動 |
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| Subtitle | 原著 |
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| Authors | 秋山潤根*, 川村隆枝*, 水間謙三**, 涌澤玲児* |
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| Authors(kana) | |
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| Organization | *岩手医科大学医学部麻酔学教室, **岩手医科大学医学部薬理学教室 |
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| Journal | 循環制御 |
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| Volume | 17 |
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| Number | 1 |
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| Page | 25-29 |
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| Year/Month | 1996/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」人工血管置換術を予定されたASA II〜IIIの患者10名を対象に, 循環停止中の局所脳内酸素飽和度(regional cerebral oxygen saturation, rSO2)を持続的に測定し, 術後中枢神経障害との関係につき比較検討した. また, 3例については同時に内頚静脈球部酸素飽和度(SjvO2)も測定した. その結果, 循環停止中のrSO2は持続的に低下し, 循環停止終了時には循環停止直前の値に比較して有意に低下した(P<0.05). 又, 中枢神経障害群の循環停止終了時のrSO2は, 非障害群の値に比較して有意に低値を示した(P<0.01). 更に, 循環停止時間70分以上, rSO260%以下となった症例6例中5例で術後中枢神経障害が認められた. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | rSO2, Circulatory arrest, Brain damage, Major vascular surgery |
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| English |
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| Title | Changes of rSO2 during Hypothermic Circulatory Arrest in Patients Undergoing Major Vascular Surgery |
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| Subtitle | |
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| Authors | Junne Akiyama, Takae Kawamura, Kenzou Mizuma*, Reiji Wakusawa |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology, School of Medicine, Iwate Medical University, *Department of Pharmacology, School of Medicine, Iwate Medical University |
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| Journal | Circulation Control |
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| Volume | 17 |
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| Number | 1 |
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| Page | 25-29 |
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| Year/Month | 1996/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | Circulatory arrest with profound hypothermia is an important surgical adjuvant that allows protected cessation of cerebral blood flow for a brief period. In 10 patients undergoing this procedure, regional cerebral oxygen saturation (rSO2) was measured continuously by optical spectroscopy. rSO2 decreased significantly at the end of circulatory arrest compared with the value of pre-circulatory arrest (P<0.05). Furthemore, rSO2 at the end of circulatory arrest in the patients who suffered from cerebral damage after operation was lower than that of other patients who did not (P<0.01). Five of 6 patinets whose rSO2 was under 60 % and circulatory arrest time last beyond 70 min, suffered from cerebral damage after operation. These findings suggest that the measurement of rSO2 during hypothermic arrest is useful for the monitor of brain ischemia. (Circ Cont 17：25〜29, 1996) |
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| Practice | Basic medicine |
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| Keywords | rSO2, Circulatory arrest, Brain damage, Major vascular surgery |
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