| Japanese |
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| Title | 高周波カテーテル・アブレーション前後における自律神経系の変動―心拍変動解析および123I-MIBG心筋シンチグラフィによる検討― |
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| Subtitle | 原著 |
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| Authors | 内藤滋人, 野上昭彦, 土屋泰弘, 岡本栄一, 外山卓二, 星崎洋, 大島茂, 湯浅和男, 谷口興一 |
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| Organization | 群馬県立循環器病センター 循環器内科 |
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| Journal | 循環制御 |
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| Volume | 17 |
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| Number | 2 |
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| Page | 197-203 |
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| Year/Month | 1996/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」上室性頻拍症例に対する高周波カテーテル・アブレーションに伴う自律神経活動の変動, 及び自律神経障害に関し, 心拍変動, 及び123I-MIBG心筋シンチグラフィを用いて検討した. 房室結節回帰頻拍(AVNRT)症例において, 副交感神経活動の指標であるHF Mesor, HF Amplitude, %RR50は, アブレーション1日後において, 処置前に比し有意に低下していた. また, アブレーション1ヵ月後においては, 上記の低下は改善していた. WPW症候群症例においては, HF Mesor, HF Amplitude, %RR50いずれもアブレーション前後において有意の変化はなかった. 123I-MIBG心筋シンチグラフィにおける集積低下は, AVNRT症例, 後中隔副伝導路症例において多く認められる傾向があった. 以上より, AVNRT症例に対するslow pathway ablationにおいて, HF Mesor, HF Amplitude, %RR50の低下で示される一過性の副交感神経機能低下症例が多く認められ, 急性期におけるparasympathetic denervationが示唆された. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | Radiofrequency catheter ablation, WPW syndrome, Atrioventricular nodal reentrant tachycardia, Heart rate variability, 123I-MIBG myocardial scintigraphy |
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| English |
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| Title | Autonomic Nervous Dysfunction after Radiofrequency Catheter Ablation in Patients with Supraventricular Tachycardia. ―Investigations about Heart Rate Variability and 123I-MIBG Myocardial Scintigraphy― |
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| Authors | Shigeto Naito, Akihiko Nogami, Yasuhiro Tsuchio, Eiichi Okamoto, Takuji Toyama, Hiroshi Hoshizaki, Shigeru Oshima, Kazuo Yuasa, Koichi Taniguchi |
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| Authors(kana) | |
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| Organization | Gunma Prefectural Cardiovascular Center |
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| Journal | Circulation Control |
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| Volume | 17 |
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| Number | 2 |
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| Page | 197-203 |
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| Year/Month | 1996/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | Patients with supraventricular taehycardia may have altered autonomic nervous tone before and after radio-frequency (RF) catheter ablation. Time and frequency domain analysis of heart rate were performed before, 1 day after and 1 month after RF ablation in 32 patients (ages 51.4±16.8) with supraventricular tachycardia using by ambulatory 24-hour Holter recordings. And123I-MIBG scintigraphy was evaluated 3-6 days after RF ablation. Twenty-Two patients had accessory pathways with AV reentrant tacycardia (WPW group), and 10 patients had AV nodal reentrant tacycardia (AVNRT group). We evaluated heart rate variobility (SD, CV, RR50) in the time domain, and high frequency (0.15 to 0.40 Hz) components (HF), low frequency (0.04 to 0.15 Hz) components (LF), and LF/HF in the frequency domain with Cosinor methods. In AVNRT group, the HF Mesor, HF Amplitude and RR50 1 day after RF ablation were significantly reduced compared with those before RF ablation (HF Mesor：498 ± 421 vs 782 ± 568 P<0.05). The 30% reduction of HF Mesor was seen in 6 patients (60 %) of AVNRT group. One month after RF ablation, the reductions of HF Mesor and HF Amplitude were recoverd. In WPW group, there were no changes on heart rate variability before and after RF ablation. The uptake of 123I-MIBG was reduced in AVNRT group compared with WPW group. Conciusions：The RF ablation to slow AV nodal pathway in patients with AVNRT alterd parasympathetic tone. We speculate that the RF ablation to AVNRT induces transient parasympathetic denervation and the reduction of autonomic nervous tone may play a role in inappropriate sinus tachycardia after RF ablation. (Circ Cont 17：197〜203, 1996) |
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| Practice | Basic medicine |
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| Keywords | Radiofrequency catheter ablation, WPW syndrome, Atrioventricular nodal reentrant tachycardia, Heart rate variability, 123I-MIBG myocardial scintigraphy |
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