| Japanese |
|---|
| Title | 終末呼気陽圧人工呼吸の臓器血液量に及ぼす影響―ドパミンの影響― |
|---|
| Subtitle | 原著 |
|---|
| Authors | 福井明, 高折益彦 |
|---|
| Authors(kana) | |
|---|
| Organization | 川崎医科大学麻酔・集中治療医学教室 |
|---|
| Journal | 循環制御 |
|---|
| Volume | 17 |
|---|
| Number | 4 |
|---|
| Page | 547-553 |
|---|
| Year/Month | 1996/ |
|---|
| Article | 原著 |
|---|
| Publisher | 日本循環制御医学会 |
|---|
| Abstract | 「要旨」今までの研究で, 調節呼吸されたイヌに終末呼気陽圧(positive end-expiratory pressure：PEEP)呼吸を負荷すれば, その圧が10cm H2Oを越えると胸腔内血液量が減少, 腹腔内血液量が増加することを認めた. この状態にドパミンを負荷することでこの移動がいかなる影響を受けるか検討した. ドパミン(15, 30μg・kg-1・min-1)は平均動脈圧と心係数を上昇させた. しかしPEEP負荷(7, 14cm H2O)によって変化した上記血液量に変化を与えなかった. すなわちPEEPによって生じた循環血液の体内血管分布は, ドパミンによって改善されなかった. |
|---|
| Practice | 基礎医学・関連科学 |
|---|
| Keywords | PEEP, Organ blood volume, Dopamine |
|---|
| English |
|---|
| Title | The Effects of Positive End-Expiratory Pressure (PEEP) on Organ Blood Volume ―Effects of Dopamine― |
|---|
| Subtitle | |
|---|
| Authors | Akira Fukui, Masuhiko Takaori |
|---|
| Authors(kana) | |
|---|
| Organization | Department of Anesthesiology and Intensive Care Medicine, Kawasaki Medical School |
|---|
| Journal | Circulation Control |
|---|
| Volume | 17 |
|---|
| Number | 4 |
|---|
| Page | 547-553 |
|---|
| Year/Month | 1996/ |
|---|
| Article | Original article |
|---|
| Publisher | Japan Society of Circulation Control |
|---|
| Abstract | In previous studies, we reported that loading of PEEP at 10 cm H2O and above on dogs under controlled ventilation remarkably decreased the blood volume in the thoracic cavity and increased the blood volume in the abdominal cavity. Dopamine (15, 30 μ・kg-1・min-1) was administered under these conditions, and its effects on hemodynamic were examined in beagle. Dopamine increased mean arterial pressure and cardiac index. However, changes in the organ blood volume induced by the PEEP loading (7, 14 cm H2O) was not affected by dopamine. It means that changes in the systemic distribution of circulating blood caused by PEEP was not improved by dopamine. (Circ Cont 17：547−553, 1996) |
|---|
| Practice | Basic medicine |
|---|
| Keywords | ) PEEP, Organ blood volume, Dopamine |
|---|