| Japanese |
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| Title | 大動脈瘤手術中のジルチアゼムによる血圧管理について |
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| Subtitle | 原著 |
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| Authors | 高木治, 谷仁介, 安宅一晃, 嶋岡英輝, 佐谷誠, 北村豊 |
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| Organization | 大阪市立総合医療センター 麻酔科, 大阪市立総合医療センター 集中治療部 |
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| Journal | 循環制御 |
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| Volume | 17 |
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| Number | 4 |
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| Page | 578-582 |
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| Year/Month | 1996/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」胸部または腹部大動脈瘤手術症例9例の血圧管理にジルチアゼムを用いた. 著明な徐脈・心抑制はなく, 血圧調節が可能であった. 内頚静脈酸素飽和度(SjvO2)は血圧低下時にも著明な変動はなく, 比較的急速な低血圧への移行時にも脳血流量(CBF)は保たれている可能性が考えられた. また, 術後神経学的合併症も認められなかった. 至適投与量など, 今後さらに詳細な検討が必要と考えられた. 以上より, 大動脈瘤症例のように, 脳や冠動脈などの血流障害を合併している恐れのある症例の血圧管理に, ジルチアゼムは有用と考えられた. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | Aortic aneurysm, Diltiazem, Internal jugular venous saturation |
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| English |
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| Title | Evaluation of Diltiazem for Control of Systemic Hypertension during Aortic Aneurysm Surgery |
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| Authors | Osamu Takaki, Yoshiyuki Tani, Kazuaki Atagi, Hideki Shimaoka, Makoto Satani, Yutaka Kitamura |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology and Intensive Care Unit, Osaka City General Hospital |
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| Journal | Circulation Control |
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| Volume | 17 |
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| Number | 4 |
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| Page | 578-582 |
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| Year/Month | 1996/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | In patients with aortic aneurysm, the incidence of co-existing myocardial or cerebral ischemia is high. In this regard, the selection of drugs to control blood pressure during aortic aneurysm surgery is important. In this study, diltiazem was administered to control systemic hypertension in 9 patients with thoracic or abdominal aortic aneurysm during the surgery. Systolic blood pressure was decreased from 157 ± 9.7 to 112.9 ± 17.5 mmHg by a continuous infusion (3.5 ± 3.4 mcg/kg/min) and an additional bolus administration (2.5, 5 or 10 mg) if necessary. However, heart rate and central venous pressure were not significantly changed by the administration, and episodes of severe bradycardia, reflective tachycardia, hypotension and ST-T wave changes were not observed in this study. Internal jugular venous hemoglobin oxygen saturation was maintained above 50% in this study, and was not significantly changed by diltiazem-induced hypotension. Complications of the cardiovascular and/or neurological systems were not observed during or after surgery. In conclusion, diltiazem may be useful for control of blood pressure in patients, care during aortic aneurysm surgery. (Circ Cont 17：578〜582, 1996) |
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| Practice | Basic medicine |
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| Keywords | Aortic aneurysm, Diltiazem, Internal jugular venous saturation |
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