| Japanese |
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| Title | イソフルラン麻酔中のhead-up tiltによる脳内酸素環境の変化 |
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| Subtitle | 原著 |
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| Authors | 藤岡丞, 水本靖, 船山忠久, 大野太郎, 稲田英一, 岡田和夫 |
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| Organization | 帝京大学医学部麻酔学講座 |
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| Journal | 循環制御 |
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| Volume | 18 |
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| Number | 2 |
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| Page | 209-212 |
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| Year/Month | 1997/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」イソフルラン麻酔中のhead-up tilt(HUT)による脳内酸素環境の変化を検討した. 1MACイソフルラン麻酔下の手術患者10名(I群)および対照群として覚醒健常人10名(A群)に10°のHUTを行い, 近赤外線分析法を用い局所脳内酸素飽和度(rSo2)の変化を5分間, および水平位に復帰させてから3分間測定した. A群ではrSo2の低下は見られなかった. I群ではHUT 1分後から水平位復帰の3分後にかけて, rSo2が低下した. HUTの4分後から水平位復帰の3分後で両群間に有意差を認めた. イソフルラン麻酔中のHUTでは覚醒時に比べて脳内酸素環境が悪化する可能性が示唆された. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | Head-up tilt, Cerebral oxygenation, Isoflurane |
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| English |
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| Title | Change of Cerebral Oxygenation in Response to Head-up Tilt under Isoflurane Anesthesia |
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| Authors | Susumu Fujioka, Kiyoshi Mizumoto, Tadahisa Funayama, Taro Ohno, Eiichi Inada, Kazuo Okada |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology, Teikyo University School of Medicine |
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| Journal | Circulation Control |
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| Volume | 18 |
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| Number | 2 |
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| Page | 209-212 |
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| Year/Month | 1997/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | We studied the change of cerebral oxygenation in response to head-up tilt under isoflurane anesthesia. The parameters including blood pressure, heart rate, end tidal CO2, percutaneous O2 saturation and cerebral oxygen saturation (rSO2) were measured. After informed consent 10 adult healthy patients undergoing elective surgery were anesthetized with 1.2% isoflurane (i.e. 1 MAC) (Group I). Ten awake adult healthy volunteers served as control (Group A). After stabilization, the position was changed from horizontal to 10 degree head-up tilt over 10 second. The head-up position was kept for 5 min, and the parameters were recorded every minute. Then the subject was retuned to the horizontal position. The parameters were measured every minute for 3 min. While the rSO2 remained constant during head-up tilt in the Group A, the rSO2 significantly decreased during head-up tilt and remained low after repositioning in the Group I. These results suggest cerebral oxygenation may be impaired in response to head-up tilt under isoflurane anesthesia. |
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| Practice | Basic medicine |
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| Keywords | Head-up tilt, Cerebral oxygenation, Isoflurane |
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