| Japanese |
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| Title | 脳外科手術に対する軽度低体温療法における冷却速度に関する検討 |
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| Subtitle | 原著 |
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| Authors | 川口昌彦*1, 坂本尚典*1, 呉原弘吉*1, 西村健司*1, 杉山信子*1, 北口勝康*1, 古家仁*1, 榊寿右*2 |
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| Organization | *1奈良県立医科大学麻酔科学教室, *2奈良県立医科大学脳神経外科学教室 |
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| Journal | 循環制御 |
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| Volume | 18 |
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| Number | 4 |
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| Page | 535-540 |
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| Year/Month | 1997/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」脳外科手術患者103例に対し術中軽度低体温療法を施行し, 冷却速度が術前及び術中のどのような因子と関係するかについて検討した. 体温は麻酔導入後, 温風式加温装置と体温調節装置にて冷却を開始し, 鼓膜温34.5℃を目標温とした. 冷却開始から最 : 低温までの時間及び温度較差から冷却速度を算出し, 1)患者因子 : 年齢, 性別, 体重, 身長, 体表面積, 体脂肪率, 体重/体表面積比率, 2)術中因子 : 冷却開始時体温, 室温, との関係を検討した. ステップワイズ回帰分析にて, 冷却速度と体重/体表面積比に有意な負の相関が認められた(F値 : 12.9, r2=0.14, p=0.0006). その他の因子は, 有意な関係は認められなかった. 軽度低体温中の冷却速度には体重/体表面積比が影響するものと考えられる. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | 脳外科手術, 軽度低体温, 冷却速度, Neurosurgery, Mild hypothermia, Cooling rate |
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| English |
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| Title | Analysis of Cooling Rate during Deliberate Mild Hypothermia for Neurosurgery |
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| Subtitle | |
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| Authors | Masahiko Kawaguchi*1, Takanori Sakamoto*1, Koukichi Kurehara*1, Kenji Nishimura*1, Nobuko Sugiyama*1, Katsuyasu Kitaguchi*1, Hitoshi Furuya*1, Toshisuke Sakaki*2 |
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| Authors(kana) | |
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| Organization | *1Departments of Anesthesiology, Nara Medical University, *2Departments of Neurosurgery, Nara Medical University |
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| Journal | Circulation Control |
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| Volume | 18 |
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| Number | 4 |
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| Page | 535-540 |
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| Year/Month | 1997/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | We induced deliberate mild hypothermia in 103 patients who underwent intracranial surgery using a water blanket and a convecting device blanket. The lowest temperature measured at the tympanic membrane was adjusted to 34.5℃. The relationship between the rate of core cooling and the following parameters was analysed : 1) patient factors ; age, sex, weight, height, body surface area, body fat, weight to surface area ratio (Wt/SA ratio), and 2) intraoperative factors ; body and room temperature. The cooling rate was inversely proportional to the Wt/SA ratio (r2=0.14, p=0.0006). There were no correlation between the cooling rate and the other factors. These results suggest that the cooling rate during deliberate mild hypothermia was mainly related to the Wt/SA ratio. |
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| Practice | Basic medicine |
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| Keywords | Neurosurgery, Mild hypothermia, Cooling rate |
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