| Japanese |
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| Title | ミルリノンの人工心肺離脱時のドパミン使用量への影響 |
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| Subtitle | 原著 |
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| Authors | 石山忠彦, 川村淳夫, 奥山克巳, 熊澤光生 |
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| Authors(kana) | |
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| Organization | 山梨医科大学麻酔科学講座 |
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| Journal | 循環制御 |
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| Volume | 21 |
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| Number | 2 |
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| Page | 164-167 |
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| Year/Month | 2000/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 小児と成人の開心術において, ミルリノン使用により人工心肺離脱時のドパミンの使用頻度と使用量に差があるかを検討した. ミルリノンは, 大動脈遮断解除後, 5μg・kg-1・min-1で10分間投与した後, 0.5μg・kg-1・min-1で持続静注した. 人工心肺からの離脱には, 適宜ドパミンを使用した. 成人においては, ミルリノンの使用により人工心肺離脱時のドパミン使用量を有意に減少させた. 一方小児例においては, ミルリノンの使用にてもドパミンの使用量を減少させなかった. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | Milrinone, Dopamine, Cardiopulmonary bypass |
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| English |
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| Title | Effects of Milrinone on Dopamine Requirement during the Weaning from Cardiopulmonary Bypass |
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| Subtitle | |
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| Authors | Tadahiko Ishiyama, Atsuo Kawamura, Katsumi Okuyama, Teruo Kumazawa |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology,Yamanashi Medical University |
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| Journal | Circulation Control |
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| Volume | 21 |
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| Number | 2 |
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| Page | 164-167 |
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| Year/Month | 2000/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | We investigated the effects of milrinone on dosage of the administered dopamine that used for weaning from cardiopulmonary bypass (CPB) and at the end of the anesthesia in twenty consecutive patients (ten adults and ten children) undergoing cardiac surgery. In the adult and child cases, patients were divided into two groups (non-milrinone group and milrinone group), respectively. In the milrinone groups, after release of aortic cross-clamp, patients received a bolus infusion of 50μg・kg-1 over 10 minutes, followed by a maintenance infusion of 0.5μg・kg-1・min-1. All patients were weaned from CPB using dopamine if necessary to achieve a systolic blood pressure over 90 mmHg in adults and over 60-70 mmHg in children, respectively. Milrinone significantly reduced dopamine dosage used for weaning from CPB in adults. On the contrary, the dosage of dopamine was comparable between non-milrinone group and milrinone group in children. Because milrinone significantly decreases the need for dopamine after CBP in adults but not children, it may improve hemodynamic condition after CPB. |
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| Practice | Basic medicine |
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| Keywords | Milrinone, Dopamine, Cardiopulmonary bypass |
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