| English |
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| Title | Plasma milrinone concentrations during continuous hemodiafiltration : A case report |
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| Subtitle | |
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| Authors | Ryu Okutani, Yoshiteru Yoshioka, Ryusuke Ueki, Chikara Tashiro |
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| Authors(kana) | |
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| Organization | Intensive Care Unit, Hyogo Medical College Hospital |
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| Journal | Circulation Control |
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| Volume | 22 |
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| Number | 2 |
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| Page | 132-134 |
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| Year/Month | 2001/ |
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| Article | Report |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | Milrinone enhances myocardial contraction and has vasodilating activity by inhibiting phosphodiesterase (PDE) in the myocardial cells, increasing cellular cAMP and inducing increased Ca2+ inflow 1,2). Some patients with severe cardiac failure require continuous hemodiafiltration (CHDF) due to complicated renal failure. We report a case in which CHDF was performed during the administration of milrinone after open heart surgery and the plasma concentration of the drug was measured. |
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| Practice | Basic medicine |
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| Keywords | Plasma milrinone concentration, Renal dysfunction, Continuous hemodiafiltration |
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