| English |
|---|
| Title | Comparison of Chronological Plot of RR Interval under Hypotensive Anesthesia:Effects of Trimetaphan, Nitroprusside and Nitroglycerin |
|---|
| Subtitle | |
|---|
| Authors | Kumiko Taira*, Marie Ishihara*, Yukiko Mukubo*, Tomoko Fukada*, Kuniaki Otsuka*, Miwako Kawamata* |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Anesthesiology, Tokyo Women's Medical University Second Hospital, **Department of Internal Medicine, Tokyo Women's Medical University Second Hospital |
|---|
| Journal | Circulation Control |
|---|
| Volume | 23 |
|---|
| Number | 1 |
|---|
| Page | 17-23 |
|---|
| Year/Month | 2002/ |
|---|
| Article | Original article |
|---|
| Publisher | Japan Society of Circulation Control |
|---|
| Abstract | Purpose： To examine morphological changes in the chronological plot of RR intervals （RR interval trendgram, RR graph） and △RR/RR ratios (△ratio graph) under GOS anesthesia treated with trimetaphan compared to nitroprusside and nitroglycerin for induced hypotension. Method： Twenty ASA I−II patients received trimetaphan （group NP, n=10） or nitroprusside （group NP, n＝10）, and five ASA II patients with hypertension or ischemic heart disease received nitroglycerin （group NG, n＝5）. ECG records were measured before anesthesia （T0）, before induced hypotension （T1）, at 20 minutes after the hypotension （T2）, and at 20 minutes after discontinuation of the hypotension （T3）. A sequence of RR intervals were obtained from the ECG records with an electric caliper for 30 seconds, and the RR graphs and the △ ratio graphs were plotted with a personal computer. Results： The administration of trimetaphan significantly decreased the amplitude on the RR graph and the △ ratio graph, under GOS anesthesia （at T2, p ＜0.05 vs. T1）. However, the administration of nitroprusside did not produce similar changes in the amplitude on the RR graph and the △ ratio graph. In the T-NP groups the amplitude of RR graph decreased by induction of anesthesia （at T1, p＜0. 05 vs. T0）, but in the NG group the amplitude of RR graph did not decrease by induction of anesthesia. Conclusion： Autonomic ganglion blocking by trimetaphan under GOS anesthesia reduces the amplitude on the RR graph and the △ ratio graph. |
|---|
| Practice | Basic medicine |
|---|
| Keywords | RR interval, trimetaphan, nitroprusside, induced hypotension |
|---|