| Japanese |
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| Title | 圧波伝播特性を2次応答モデルで解析する |
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| Subtitle | 原著 |
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| Authors | 林和子 |
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| Organization | 京都府立医科大学麻酔学教室 |
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| Journal | 循環制御 |
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| Volume | 24 |
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| Number | 3 |
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| Page | 239-248 |
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| Year/Month | 2003/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」大動脈-橈骨動脈間の圧波形伝達特性を, 大動脈の特性インピーダンス, 慣性, 末梢血管抵抗, コンプライアンスの4要素を用いた2次応答モデルの周波数応答に近似した. 4要素の各々を変化させることで, さまざまな動脈特性を想定できる. それぞれの動脈特性設定下で, 伝達関数, 並びに末梢への圧波形伝搬に及ぼす影響を検討した. 4要素は, それぞれが生理的な意味合いを内包するので, この解析により, 血行動態と心臓近位側-心臓遠位側間の圧波伝達変化との因果関係を明らかにすることができる. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | 動脈圧波形, 伝達関数, ウィンドケッセルモデル, 2次応答, 圧波伝達, Arterial pressure wave, Generalized transfer function, Windkessel model, Second order response, Simulation |
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| English |
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| Title | The Analysis of Pressure Wave Transmission Using the Second-order Response Model |
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| Subtitle | |
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| Authors | Kazuko Hayashi |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology, Kyoto Prefectural University of Medicine |
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| Journal | Circulation Control |
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| Volume | 24 |
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| Number | 3 |
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| Page | 239-248 |
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| Year/Month | 2003/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | The transfer function between aortic pressure and radial artery pressure can be approximated with second-order response system. Pressure wave deformation between aortic pressure waveforms(APW)and radial pressure wave forms(RPW)was quantitatively analyzed with a 4-element model consisting of aortic characteristic impedance(Zc), inertance(L), peripheral resistance(Rp), and compliance(C), which shows the nature of second-order response, to clarify the physiological background of cardiovascular conditions accounting for pressure wave distortion. Therefore, we have provided a theoretical framework to simulate the change in shapes of arterial blood pressure waves using the four parameter(Zc, L, Rp, C), corresponding to the systemic circulation. The results suggest that large aortic impedance, low peripheral resistance, and increased compliance cause the damping of RPW. The model approach enables us to recognize the physiological causality of pressure wave deformation in relation to the cardiovascular conditions. |
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| Practice | Basic medicine |
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| Keywords | Arterial pressure wave, Generalized transfer function, Windkessel model, Second order response, Simulation |
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