| English |
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| Title | Anaphylactoid Shock Caused by 5% Human Serum Albumin Transfusion |
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| Subtitle | |
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| Authors | Takashi Tsunetoh, Ryu Okutani, Mariko Masutani, Tomoko Koshimichi |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology, Osaka City General Hospital |
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| Journal | Circulation Control |
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| Volume | 30 |
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| Number | 1 |
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| Page | 45-47 |
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| Year/Month | 2009/5 |
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| Article | Report |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | [Abstract] A 38-year-old woman underwent bilateral adnexectomy and partial omentectomy procedures for diagnosed ovarian cancer, and developed anaphylactoid shock after administration of 5% human serum albumin (HSA). She had no history of drug or food allergic reactions, nor any previous blood transfusions. Immediately after 5% HSA transfusion, blood pressure dropped to 60/35mmHg and heart rate increased to 100bpm. On the basis of her clinical course, we concluded that albumin had induced anaphylactoid shock. Consequently, we discontinued the albumin product transfusion and administered epinephrine, after which the symptoms improved. The concentration of plasma tryptase was remarkably elevated to 64.1μg・l-1 at 1 hour after the occurrence of symptoms. |
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| Practice | Basic medicine |
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| Keywords | anaphylactoid shock, 5% human serum albumin, tryptase |
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