| Japanese |
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| Title | 心拍動下冠動脈バイパス術周術期にCarperitide投与が著効した非透析高度腎機能低下患者の1例 |
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| Subtitle | 症例 |
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| Authors | 糸井亜衣*1,*2, 山南将志*1, 木谷公紀*1, 土肥正浩*1, 小川貢*1, 大川和成*1, 土井潔*1, 森反俊幸*2, 夜久均*1 |
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| Authors(kana) | |
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| Organization | *1京都府立医科大学心臓血管外科, *2鈴鹿医療科学大学医用工学部臨床工学科 |
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| Journal | 循環制御 |
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| Volume | 32 |
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| Number | 2 |
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| Page | 101-104 |
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| Year/Month | 2011/8 |
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| Article | 報告 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「緒言」冠動脈バイパス術(CABG)は手術手技の向上や周術期管理の進歩により安全な手術として確立されている. しかし, 高齢化および冠状動脈インターベンションの発展などに伴い, CABGの対象は合併疾患を有する例が多く占めるようになり1, 2), 腎機能低下例に対するCABGも余儀なくされている. 近年, 手術の低侵襲化を図るために人工心肺を使用しない心拍動下冠動脈バイパス術(OPCAB)が普及しており3, 4), OPCABは術前腎機能の温存に有用であるとの報告がある5〜7). また, 術中からのcarperitide (hANP)投与が周術期の腎保護に有効との報告がある8〜10). 今回, 術前腎機能低下患者に対しOPCAB施行時からhANP投与を行い, 腎機能を温存でき術後経過が良好であった1例を経験した. 「症例」症例は76歳, 男性. 身長168cm, 体重63kg, 体表面積(BSA)1.71m2. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | human atrial natriuretic peptide, renal failure, renoprotective effect, cardiac surgery, off-pump coronary artery bypass grafting |
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| English |
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| Title | The Efficacy of Carperitide in a Patient with Severe Renal Dysfunction Undergoing Off-Pump Coronary Artery Bypass Grafting: A Case Report |
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| Subtitle | |
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| Authors | Ai Itoi*1,*2, Masashi Yamanami*1, Kimitoshi Kitani*1, Masahiro Dohi*1, Mitsugu Ogawa*1, Kazunari Okawa*1, Kiyoshi Doi*1, Toshiyuki Moritan*2, Hitoshi Yaku*1 |
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| Authors(kana) | |
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| Organization | *1Department of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, *2Clinical Engineering, Faculty of Medical Engineering, Suzuka University of Medical Science |
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| Journal | Circulation Control |
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| Volume | 32 |
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| Number | 2 |
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| Page | 101-104 |
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| Year/Month | 2011/8 |
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| Article | Report |
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| Publisher | Japan Society of Circulation Control in Medicine |
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| Abstract | A 76-year-old man presented to our hospital with chest pain and dyspnea. Coronary angiography revealed a 90% stenosis in the left main trunk, 90% stenosis in the left circumflex artery, and total occlusion in the right coronary artery. He was also diagnosed as having severe renal dysfunction with serum Cr 3.93mg/dl, eGFR 12.5ml/min/1.73m2 and Ccr 19.3ml/min. He underwent OPCAB, and carperitide was administered during the operation and continued until the 8 POD. The combined therapy of OPCAB and carperitide infusion were effective for protection of renal function during and after the operation. The urine output and renal function were maintained at the same level as the pre-operation values during and after the operation. |
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| Practice | Basic medicine |
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| Keywords | human atrial natriuretic peptide, renal failure, renoprotective effect, cardiac surgery, off-pump coronary artery bypass grafting |
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