| Japanese |
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| Title | サリンヘス(R)の循環維持効率 |
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| Subtitle | 原著 |
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| Authors | 小川龍*, 福田功*, 尾藤博保*, 大井良之* |
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| Organization | *日本医科大学麻酔科学教室 |
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| Journal | 循環制御 |
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| Volume | 11 |
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| Number | 1 |
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| Page | 107-111 |
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| Year/Month | 1990/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」生理的食塩液に溶解された, 血漿と等しい膠質浸透圧をもつハイドロキシエチル澱粉液(サリンヘス(R))の硬膜外麻酔時の循環維持効果を乳酸リンゲル液と比較した. 実験群の成人婦人の子宮筋腫摘出患者に, 手術開始より1時間にサリンヘス(R)を1l投与し, 後必要に応じて乳酸リンゲル液を投与した. 対照群には乳酸リンゲル液のみを投与した. 結果はサリンヘス群の循環維持効果が対照群より優れ, 輸液総量が低く保たれた. またサリンヘス(R)を同じ条件で投与された乳酸リンゲル液に溶解された同濃度のハイドロキシエチル澱粉液(ヘスパンダー(R))と比較したが, 循環維持効果は同等であり, 術後の血漿電解質なども差が見られなかった. これより, サリンヘス(R)はヘスパンダー(R)同様術中の循環血液量維持の目的で使用できる. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | hydroxyethyl starch, Ringer's lactate solution, fluid therapy, epidural block |
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| English |
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| Title | Efficiency of Salinhes(R) to maintain hemodynamics during epidural anesthesia |
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| Subtitle | |
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| Authors | Ryo Ogawa, Isao Hukuda, Hiloyasu Bitoh, Yosiyuki Ohi |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology Nippon Medical School |
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| Journal | Circulation Control |
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| Volume | 11 |
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| Number | 1 |
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| Page | 107-111 |
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| Year/Month | 1990/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | The efficiency of Salinhes(R), a 6% solution of hydroxyethyl starch, Ringer's lactate solution, fluid therapy, epidural block hydroxyethyl starch (HES) dissolved in saline, to maintain hemodynamics was compared to Ringer's lactate solution (RLS) during epidural anesthesia. Twenty nine women undergoing total abdominal hysterectomy were divided into 3 groups. Patients in the 1st group were infused with RLS to maintain hemodynamic during epidural anesthesia. Patients in the 2nd group received 1 liter of Hespander(R), a 6% solution of HES dissolved in RLS, in the first one hour of anesthesia and necessary RLS was followed afterward. Patients in the 3rd group were infused with one liter of Salinhes(R) in the first one hour of anesthesia and RLS was followed as same as in the 2nd group. The total amount of infused solution in the lst group was greater than in 2nd and 3rd groups. The frequency of vasopressor injection during anesthesia were more in 1st group than in 2nd and 3rd groups. There was no difference in plasma electrolyte contents between groups with Salinhes(R) or Hespander(R) at the end of anesthesia. The results suggest that colloid solution, Salinhes(R), were more efficient than crystalloid solution to maintain hemodynamics without disturbance of plasma electrolytes in the limited amounts. |
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| Practice | Basic medicine |
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| Keywords | hydroxyethyl starch, Ringer's lactate solution, fluid therapy, epidural block |
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