| Japanese |
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| Title | 急速少量脱血後の血圧回復に及ぼす因子について |
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| Subtitle | 原著 |
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| Authors | 與座浩次* |
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| Authors(kana) | |
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| Organization | *琉球大学医学部麻酔科学教室 |
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| Journal | 循環制御 |
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| Volume | 12 |
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| Number | 4 |
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| Page | 685-690 |
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| Year/Month | 1991/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」雑種成犬を単純脱血群(I群), 両側頚動脈洞-大動脈神経切断後脱血群(H群), 両側副腎摘出後脱血群(III群)に分け, 循環血液量の約4%の少量脱血を2〜5秒間に急速に行った. 3群とも, 急速少量脱血後平均動脈圧は急速かつ有意の低下が起こった. その後I群では急速な血圧回復, 続いて緩徐な血圧回復が認められた. 一方II群では, 脱血直後の急速な血圧回復が認められず, 緩徐な血圧回復のみであった. また, III群では急速な血圧回復は認められたものの, その後の緩徐な血圧回復が認められなかった. 血圧と同時に血漿エピネフリン, ノルエピネフリン濃度を測定した結果, 有意な変化は示さなかった. しかし, 全体の傾向としてI群では, 脱血後早期より血圧の変化とほぼ鏡面像的に反応していた. II群では, 緩徐な回復時期にもE, NE濃度の上昇がみられ, 副腎由来と考えられるE, NEは, 脱血後早期から反応するが, 平均動脈圧の回復に影響するのは緩徐な血圧回復期であろうと考えられた. III群では, ほとんど変化が見られなかった. 以上より, 急速少量脱血後の血圧回復には, 早期には両側頚動脈洞-大動脈神経を介する反射系が関与し, 続いて副腎を介する反射系が血圧回復に関与するものと示唆された. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | Hemorrhage, Barorecepter, Epinephrine, Norepinephrine |
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| English |
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| Title | The factors of restoration of blood pressure after acute and a small amount of hemorrhage in dogs |
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| Subtitle | |
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| Authors | Kouji Yoza |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology Faculty of Medicine University of the Ryukyus |
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| Journal | Circulation Control |
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| Volume | 12 |
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| Number | 4 |
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| Page | 685-690 |
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| Year/Month | 1991/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | We investigated the factors that restored blood pressure after acute (2〜5 seconds) and a small amount of hemorrhage (4% of total blood volume) in dogs. The 29 adult mongrel dogs were divided 3 groups as follows. The dogs in group I were intact, in group II were cut bilateral sino-aortic nerves and in group III were bilateral adrenalectomied. They were anesthetized with Air-Oxygen-Enflurane. We measured the mean arterial pressure (MAP) and the concentrations of epiriephrine (E) and norepinephrine (NE) in plasma. In all groups, the MAP declined acutely after hemorrhage. After that, it ascended independently. In group I, it acutely ascended and then slowly. In group II, it slowly ascended without acute ascent. In group III, it acutely ascended, but then it was stagnant without slow ascent. The concentrations of E and NE did not change significantly in all Groups. But in group II, that had a tendency to increase when its MAP slowly ascended. We submit that the sino-aortic baroreflex system plays important role when the MAP acutely ascends after a little hemorrhage and the role of adrenal medulla in hemodynamic response to hemorrhage is important when the MAP slowly ascends after acute ascent. |
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| Practice | Basic medicine |
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| Keywords | Hemorrhage, Barorecepter, Epinephrine, Norepinephrine |
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