| Japanese |
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| Title | イヌにおける硬膜外麻酔中の高二酸化炭素血症は左室収縮機能を低下させる―心エコー法による検討― |
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| Subtitle | 原著 |
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| Authors | 米田高宏 |
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| Authors(kana) | |
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| Organization | 金沢大学医学部麻酔・蘇生学教室 |
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| Journal | 循環制御 |
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| Volume | 16 |
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| Number | 4 |
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| Page | 556-561 |
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| Year/Month | 1995/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」硬膜外麻酔中の高二酸化炭素血症が, 左室収縮機能を低下させるか否かについて検討した. 16頭の雑種イヌを硬膜外麻酔群(n=8)と対照群(n=8)に分け, 85%O2/15%CO2混合ガスの吸入(PaCO2〜100mmHg)前後における経胸壁心エコー所見およびその他の循環動態の各指標を比較した. 硬膜外麻酔群では, 混合ガスの吸入により前負荷の指標である左室拡張終末期容積/体表面積(EDV/BSA)は変化しなかったが, 駆出分画は39±11%(平均値±標準偏差)から25±11%に低下した(P＜0.05). 一方, 混合ガスの吸入により対照群のEDV/BSAは吸入前の142%前後に上昇したが(P<0.05), 駆出分画は変化しなかった. 以上から, 硬膜外麻酔中の高二酸化炭素血症は, 左室収縮機能を低下させると結論された. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | Carbon dioxide, Cardiac pump function, Echocardiography, Epidural anesthesia, Hypercapnia. |
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| English |
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| Title | Cardiac Pump Function Is Depressed by Hypercapnia and Epidural Anesthesia in Dogs. |
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| Subtitle | |
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| Authors | Takahiro Yoneda |
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| Authors(kana) | |
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| Organization | Department of Anesthesiology, and Intensive Care Medicine, Kanazawa University, School of Medicine |
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| Journal | Circulation Control |
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| Volume | 16 |
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| Number | 4 |
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| Page | 556-561 |
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| Year/Month | 1995/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | The purpose of the present study was to investigate whether the combination of hypercapnia and epidural anesthesia would depress cardiac function. Sixteen adult mongrel dogs were anesthetized with halothane and ventilated mechanically. They were randomly assigned to epidural anesthesia group (n=8) or control group (n=8) according to with or without epidural anesthesia. The end-diastolic volume per body surface area (EDV/BSA) and ejection fraction (EF) of the left ventricle were measured with pericordial echocardiography. By the administration of hypercapnia (PaCO2〜100 mmHg) for 5 min, the group of epidural anesthesia did not show significant changes in EDV/BSA, but showed a decrease in EF from 39±11 (SD)% to 25±11% (P<0.05). On the other hand, the control group exhibited an increase in EDV/BSA to 142% by the hypercapnia (P<0.05), but did not exhibit significant changes in the EF. It is concluded that hypercapnia during epidural anesthesia depresses the cardiac pump function in dogs. (Circ Cont 16：556〜561, 1995) |
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| Practice | Basic medicine |
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| Keywords | Carbon dioxide, Cardiac pump function, Echocardiography, Epidural anesthesia, Hypercapnia. |
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