| Japanese |
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| Title | Pressure guide wireにおけるcollateral flowと心電図変化の検討 |
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| Authors | 高間典明*, 外山卓二*, 小板橋紀通*, 直田匡彦*, 中津川昌利*, 川上武*, 堀江康人*, 廣井知歳*, 磯部直樹*, 夛田浩*, 安達仁*, 内藤滋人*, 野上昭彦*, 星崎洋*, 大島茂*, 谷口興一* |
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| Authors(kana) | |
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| Organization | *群馬県立循環器病センター循環器内科 |
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| Journal | 循環制御 |
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| Volume | 20 |
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| Number | 4 |
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| Page | 410-414 |
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| Year/Month | 1999/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」Pressure guide wire(PGW)は近年開発された新しい手法の1つである. 本研究では心筋虚血のpreconditioning効果とPGWを用いて測定したcollateral flowとの関係を検討した. そしてcollateral flowを冠状動脈完全閉塞状態の補充可能最大側副血流量(Qc/QN)から評価し, 冠状動脈完全閉塞時に心電図上2mm以上のST上昇を伴う高度虚血群と2mm未満の軽度虚血群の二群間での相違を比較した. 結果として冠状動脈完全閉塞時のST上昇の総和とQc/QNは負の良好な相関を示し, 更に高度虚血群では軽度虚血群に比較してQc/QNは有意に低値を示した(P<0.05). 冠状動脈完全閉塞時の心筋虚血緩和にはcollateral flowが直接関与しているものと考えられた. |
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| Practice | 基礎医学・関連科学 |
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| English |
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| Title | A Comparison of Electrocardiographic Change with Collateral Flow Using Pressure Guide Wire |
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| Authors | Noriaki Takama*, Takuji Toyama*, Norimichi Kohabashi*, Masahiko Suguta*, Masatoshi Nakatsugawa*, Takeshi Kawakami*, Yasuto Horie*, Chitoshi Hiroi*, Naoki Isobe*, Hiroshi Tada*, Hitoshi Adachi*, Shigeto Naito*, Akihiko Nogami*, Hiroshi Hoshizaki*, Shigeru Oshima*, Koichi Taniguchi* |
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| Authors(kana) | |
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| Organization | *Cardiology Division, Gunma Prefectural Cardiovascular Center |
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| Journal | Circulation Control |
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| Volume | 20 |
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| Number | 4 |
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| Page | 410-414 |
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| Year/Month | 1999/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | The purpose of this study was to examine the relation between preconditioning and collateral flow calculated by pressure guide wire (PGW) in patient with ischemic heart disease. A recruitable fractional collateral flow (Qc/QN) in occluded coronary artery is important to evaluate collateral flow, therefore we compared Qc/QN between severe ischemic group which had more than 2 mm ST elevation and mild ischemic group which had less than 2mm ST elevation in electrocardiogram, As a result, Qc/QN correlated negatively with the sum of ST elevation, and Qc/QN of severe ischemic group was significantly lower than that of mild ischemic group. We conclude that collateral flow directly relieves myocardial ischemia in occluded coronary artery. |
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| Practice | Basic medicine |
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| Keywords | Pressure guide wire (PGW), Preconditioning, Recruitable fractional collateral flow (Qc/QN), Collateral flow |
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