| Japanese |
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| Title | 開心術後急性期における一過性頻脈性心房細動出現に関するナトリウム利尿ペプチドの関連性 |
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| Subtitle | 原著 |
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| Authors | 渡辺正明, 浜田修三 |
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| Organization | 福島県立会津総合病院心臓血管外科 |
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| Journal | 循環制御 |
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| Volume | 21 |
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| Number | 4 |
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| Page | 434-439 |
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| Year/Month | 2000/ |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 術前洞調律である待期的開心術症例において術後一過性頻脈性心房細動出現症例におけるナトリウム利尿ペプチド(ANP, BNP)を術後7日目まで測定し, 非出現例と比較検討を行った. 頻脈性心房細動出現は術後2日目後半から出現し反復する症例もあったが, ほぼ全症例において心房細動出現以前にANPおよびBNPは最高値を示した. BNP/ANP値は体外循環中から心房細動出現例で有意に上昇し, 術後7日目でも有意に高値を維持した. 肺動脈カテーテルを用いた循環動態の検討から心室機能低下に対する容量・圧負荷が頻脈性心房細動出現に大きく関与し, また反復する頻脈性心房細動が一旦上昇したANP, BNP濃度高値を維持していると推測された. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | Atrial fibrillation, Atrial natriuretic peptide, Brain natriuretic peptide |
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| English |
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| Title | The Relationship between Natriuretic Peptide and Atrial Fibrillation with Tachycardia on Acute Phase after Cardiac Surgery |
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| Authors | Masaaki Watanabe, Osami Hamada |
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| Authors(kana) | |
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| Organization | The Division of Cardiovascular Surgery,Fukushima Prefectural Aizu General Hosoital |
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| Journal | Circulation Control |
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| Volume | 21 |
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| Number | 4 |
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| Page | 434-439 |
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| Year/Month | 2000/ |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control |
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| Abstract | Atrial fibrillation with tachycadia (af-T) is a common postoperative complication after cardiac surgery. It is induced by acute atrial enlargement, atrial infarction, atrial hypertension and trauma due to cannulation, etc. Atrial natriuretic peptide (ANP) is mainly produced in the atria and brain natriuretic peptide (BNP) in the ventricles. It is considered that these hormones are secreted as a compensatory reaction to pre- and postload pressure elevation and fluid accumulation. We, therefore, studied the relationship between plasma levels of natriuretic peptides (ANP and BNP) and the onset of af-T after cardiac surgery. MPWP and mRAP were higher and LVSWI, RVSWI and RVEF were lower in af-T patients on postoperative days 1 to 2. Most episodes of af-T occurred on postopeartive days 2 to 3 and peak plasma levels of ANP and BNP appeared before onset of af-T. BNP/ANP was higher from cardiopulmonary bypass and continued until 7th postoperative day significantly in comparison with patients of normal sinus rhythm. We found af-T after cardiac surgery caused pre- and postload pressure elevation and fluid accumulation and repeated or continuous af-T revealed high plasma levels of ANP and BNP at the 7th postoperative day. |
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| Practice | Basic medicine |
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| Keywords | Atrial fibrillation, Atrial natriuretic peptide, Brain natriuretic peptide |
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