| Japanese |
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| Title | 成人心臓外科手術におけるModified Ultrafiltrationの有用性 |
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| Subtitle | 原著 |
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| Authors | 澤田敦史, 枝長充隆, 宮下龍, 山蔭道明 |
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| Organization | 札幌医科大学医学部麻酔科学講座 |
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| Journal | 循環制御 |
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| Volume | 33 |
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| Number | 3 |
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| Page | 199-203 |
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| Year/Month | 2012/12 |
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| Article | 原著 |
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| Publisher | 日本循環制御医学会 |
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| Abstract | 「要旨」2010年1月から2011年2月までに開心術・大血管手術を施行された成人患者70症例を対象に, 成人心臓血管外科手術におけるModified ultrafiltration(MUF)の有用性を後ろ向きに検討した. MUF施行により収縮期血圧は有意に上昇した. MUF施行群は, 少ない赤血球濃厚液投与量で, 体外循環前後および体外循環終了後のヘマトクリット値をMUF非施行群とほぼ同等に保つことができた. MUF群は, MUF非施行群と比較して, 晶質液および膠質液の投与量も有意に少なかった. 本研究の結果から, MUFは小児開心術に限らず, 成人心臓外科手術においても有用であることが示唆された. |
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| Practice | 基礎医学・関連科学 |
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| Keywords | hemodynamic function, systolic blood pressure, hematocrit |
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| English |
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| Title | Usefulness of Modified Ultrafiltration to Adult Patients after Cardiovascular Surgery |
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| Subtitle | |
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| Authors | Atsushi Sawada, Mitsutaka Edanaga, Ryo Miyashita, Michiaki Yamakage |
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| Organization | Anesthesiology, Sapporo Medical University School of Medicine |
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| Journal | Circulation Control |
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| Volume | 33 |
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| Number | 3 |
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| Page | 199-203 |
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| Year/Month | 2012/12 |
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| Article | Original article |
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| Publisher | Japan Society of Circulation Control in Medicine |
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| Abstract | [Introduction:] Modified ultrafiltration (MUF) can remove excess water and inflammatory mediators from the circulation after cardiopulmonary bypass (CPB) in pediatric patients. However, the value of MUF in adult patients remains unknown. [Methods:] We retrospectively investigated hemodynamic functions after MUF in 70 adult patients who had undergone cardiovascular surgery. [Results:] Systolic blood pressure was significantly increased after MUF. The hematocrit after CPB decreased in the control, but not in the MUF group. The MUF group required less red blood cell products, colloids and crystalloid solution resuscitation than the control group. No adverse events were associated with MUF. [Discussion:] Modified ultrafiltration can safely achieve hemoconcentration, resulting in increases of systolic blood pressure after CPB, less intraoperative red blood cell transfusion and lower postoperative fluid resuscitation. [Conclusion:] Modified ultrafiltration can improve hemodynamic function and diminish transfusion requirements not only for pediatric, but also for adult patients. |
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| Practice | Basic medicine |
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| Keywords | hemodynamic function, systolic blood pressure, hematocrit |
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